PDGFD antibody

Catalog No. ABIN7117563

This anti-PDGFD antibody is a Rabbit Polyclonal antibody detecting PDGFD in WB, ELISA and IHC. Suitable for Human, Mouse and Rat.

Quick Overview for PDGFD antibody (ABIN7117563)

Target: PDGFD (Platelet Derived Growth Factor D (PDGFD))

Reactivity: Human, Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This PDGFD antibody is un-conjugated

Application: Western Blotting (WB), ELISA, Immunohistochemistry (IHC)

Product Details anti-PDGFD Antibody

Purpose: PDGFD antibody

Purification: Immunogen affinity purified

Purity: ≥95 % as determined by SDS-PAGE

Immunogen: platelet derived growth factor D

Isotype: IgG

Application Details

Application Notes: WB: 1:500-1:2000, IHC: 1:20-1:200

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: PBS with 0.02 % sodium azide and 50 % glycerol pH 7.3,

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freeze / thaw cycles.

Storage: -20 °C

Storage Comment: -20°C for 12 months

Expiry Date: 12 months

Target Details for PDGFD

Target: PDGFD (Platelet Derived Growth Factor D (PDGFD))

Alternative Name: PDGFD

Background:

Synonyms: Platelet-derived growth factor D (PDGF-D)|Iris-expressed growth factor|Spinal cord-derived growth factor B (SCDGF-B)|Platelet-derived growth factor D, latent form (PDGFD latent form)|Platelet-derived growth factor D, receptor-binding form (PDGFD receptor-binding form)|PDGFD|IEGF|SCDGFB

Background: Growth factor that plays an essential role in the regulation of embryonic development, cell proliferation, cell migration, survival and chemotaxis. Potent mitogen for cells of mesenchymal origin. Plays an important role in wound healing. Induces macrophage recruitment, increased interstitial pressure, and blood vessel maturation during angiogenesis. Can initiate events that lead to a mesangial proliferative glomerulonephritis, including influx of monocytes and macrophages and production of extracellular matrix(By similarity).

Molecular Weight: 43 kDa, 27 kDa

Gene ID: 80310

UniProt: Q9GZP0

Pathways: RTK Signaling, Platelet-derived growth Factor Receptor Signaling