PQBP1 antibody

Catalog No. ABIN7117652

The Rabbit Polyclonal anti-PQBP1 antibody has been validated for WB and ELISA. It is suitable to detect PQBP1 in samples from Human, Mouse and Rat.

Quick Overview for PQBP1 antibody (ABIN7117652)

Target: PQBP1 (Polyglutamine Binding Protein 1 (PQBP1))

Reactivity: Human, Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This PQBP1 antibody is un-conjugated

Application: Western Blotting (WB), ELISA

Product Details anti-PQBP1 Antibody

Purification: Immunogen affinity purified

Purity: ≥95 % as determined by SDS-PAGE

Immunogen: polyglutamine binding protein 1

Isotype: IgG

Application Details

Application Notes: WB: 1:500-1:2000

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: PBS with 0.02 % sodium azide and 50 % glycerol pH 7.3,

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: -20°C for 12 months (Avoid repeated freeze / thaw cycles.)

Expiry Date: 12 months

Target Details for PQBP1

Target: PQBP1 (Polyglutamine Binding Protein 1 (PQBP1))

Alternative Name: PQBP1

Background: Synonyms:NPW38 Background:Probably functions as scaffold protein that is part of numerous complexes and thereby plays a role in pre-mRNA splicing, transcription regulation and neuron development. Required for normal alternative splicing of target pre-mRNA species(PubMed:23512658). May suppress the ability of POU3F2 to transactivate the DRD1 gene in a POU3F2 dependent manner. Can activate transcription directly or via association with the transcription machinery. May be involved in ATXN1 mutant-induced cell death. The interaction with ATXN1 mutant reduces levels of phosphorylated RNA polymerase II large subunit.

Molecular Weight: 38 kDa, 30 kDa

Gene ID: 10084

UniProt: O60828

Pathways: Ribonucleoprotein Complex Subunit Organization