POLR2C antibody

Catalog No. ABIN7117671

This anti-POLR2C antibody is a Rabbit Polyclonal antibody detecting POLR2C in WB, IHC, ELISA and IP. Suitable for Human, Mouse and Rat.

Quick Overview for POLR2C antibody (ABIN7117671)

Target: POLR2C (Polymerase (RNA) II (DNA Directed) Polypeptide C, 33kDa (POLR2C))

Reactivity: Human, Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This POLR2C antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (IHC), ELISA, Immunoprecipitation (IP)

Product Details anti-POLR2C Antibody

Purpose: POLR2C antibody

Purification: Immunogen affinity purified

Purity: ≥95 % as determined by SDS-PAGE

Immunogen: polymerase(RNA) II(DNA directed) polypeptide C, 33kDa

Isotype: IgG

Application Details

Application Notes: WB: 1:500-1:2000, IP: 1:200-1:1000, IHC: 1:20-1:200

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: PBS with 0.02 % sodium azide and 50 % glycerol pH 7.3,

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freeze / thaw cycles.

Storage: -20 °C

Storage Comment: -20°C for 12 months

Expiry Date: 12 months

Target Details for POLR2C

Target: POLR2C (Polymerase (RNA) II (DNA Directed) Polypeptide C, 33kDa (POLR2C))

Alternative Name: POLR2C

Background:

Synonyms: DNA-directed RNA polymerase II subunit RPB3 (RNA polymerase II subunit 3, RNA polymerase II subunit B3)|DNA-directed RNA polymerase II 33 kDa polypeptide (RPB33)|DNA-directed RNA polymerase II subunit C|RPB31|POLR2C

Background: DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. Component of RNA polymerase II which synthesizes mRNA precursors and many functional non-coding RNAs. Pol II is the central component of the basal RNA polymerase II transcription machinery. It is composed of mobile elements that move relative to each other. RPB3 is part of the core element with the central large cleft and the clamp element that moves to open and close the cleft(By similarity).

Molecular Weight: 33 kDa

Gene ID: 5432

UniProt: P19387

Pathways: Regulatory RNA Pathways