POLR2I antibody

Catalog No. ABIN7117676

The Rabbit Polyclonal anti-POLR2I antibody has been validated for WB and ELISA. It is suitable to detect POLR2I in samples from Human, Mouse and Rat.

Quick Overview for POLR2I antibody (ABIN7117676)

Target: POLR2I (Polymerase (RNA) II (DNA Directed) Polypeptide I, 14.5kDa (POLR2I))

Reactivity: Human, Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This POLR2I antibody is un-conjugated

Application: Western Blotting (WB), ELISA

Product Details anti-POLR2I Antibody

Purpose: POLR2I antibody

Purification: Immunogen affinity purified

Purity: ≥95 % as determined by SDS-PAGE

Immunogen: polymerase(RNA) II(DNA directed) polypeptide I, 14.5kDa

Isotype: IgG

Application Details

Application Notes: WB: 1:500-1:2000

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: PBS with 0.02 % sodium azide and 50 % glycerol pH 7.3,

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freeze / thaw cycles.

Storage: -20 °C

Storage Comment: -20°C for 12 months

Expiry Date: 12 months

Target Details for POLR2I

Target: POLR2I (Polymerase (RNA) II (DNA Directed) Polypeptide I, 14.5kDa (POLR2I))

Alternative Name: POLR2I

Background:

Synonyms: DNA-directed RNA polymerase II subunit RPB9 (RNA polymerase II subunit B9)|DNA-directed RNA polymerase II subunit I|RNA polymerase II 14.5 kDa subunit (RPB14.5)|POLR2I

Background: DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. Component of RNA polymerase II which synthesizes mRNA precursors and many functional non-coding RNAs. Pol II is the central component of the basal RNA polymerase II transcription machinery. It is composed of mobile elements that move relative to each other. RPB9 is part of the upper jaw surrounding the central large cleft and thought to grab the incoming DNA template(By similarity).

Molecular Weight: 15 kDa

Gene ID: 5438

UniProt: P36954

Pathways: Regulatory RNA Pathways