PRR5 antibody
-
- Target See all PRR5 Antibodies
- PRR5 (Proline Rich 5 (Renal) (PRR5))
-
Reactivity
- Human, Mouse, Rat
-
Host
- Rabbit
-
Clonality
- Polyclonal
-
Conjugate
- This PRR5 antibody is un-conjugated
-
Application
- Western Blotting (WB), ELISA, Immunohistochemistry (IHC), Immunofluorescence (IF), Immunoprecipitation (IP)
- Purification
- Immunogen affinity purified
- Purity
- ≥95 % as determined by SDS-PAGE
- Immunogen
- proline rich 5(renal)
- Isotype
- IgG
- Top Product
- Discover our top product PRR5 Primary Antibody
-
anti-Proline Rich 5 (Renal) (PRR5) (AA 109-388) antibody
PRR5 Reactivity: Human WB, IHC, IF Host: Rabbit Polyclonal unconjugated
anti-Proline Rich 5 (Renal) (PRR5) (AA 277-305), (C-Term) antibodyPRR5 Reactivity: Mouse WB Host: Rabbit Polyclonal RB40277 unconjugated
anti-Proline Rich 5 (Renal) (PRR5) (AA 35-84) antibodyPRR5 Reactivity: Human, Horse, Cow, Dog, Rabbit, Pig, Monkey WB Host: Rabbit Polyclonal unconjugated
anti-Proline Rich 5 (Renal) (PRR5) (C-Term) antibodyPRR5 Reactivity: Human, Horse WB Host: Rabbit Polyclonal unconjugated
anti-Proline Rich 5 (Renal) (PRR5) (N-Term) antibodyPRR5 Reactivity: Human WB Host: Rabbit Polyclonal unconjugated
anti-Proline Rich 5 (Renal) (PRR5) (N-Term) antibodyPRR5 Reactivity: Human, Mouse, Rat, Horse, Cow, Dog, Rabbit, Guinea Pig WB Host: Rabbit Polyclonal unconjugated
-
- Application Notes
- WB: 1:500-1:2000, IP: 1:200-1:1000, IHC: 1:20-1:200, IF: 1:20-1:200
- Restrictions
- For Research Use only
-
- Format
- Liquid
- Buffer
- PBS with 0.02 % sodium azide and 50 % glycerol pH 7.3,
- Preservative
- Sodium azide
- Precaution of Use
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Storage
- -20 °C
- Storage Comment
- -20°C for 12 months (Avoid repeated freeze / thaw cycles.)
- Expiry Date
- 12 months
-
- Target
- PRR5 (Proline Rich 5 (Renal) (PRR5))
- Alternative Name
- PRR5 (PRR5 Products)
- Background
- Synonyms:PROTOR1 Background:Subunit of mTORC2, which regulates cell growth and survival in response to hormonal signals. mTORC2 is activated by growth factors, but, in contrast to mTORC1, seems to be nutrient-insensitive. mTORC2 seems to function upstream of Rho GTPases to regulate the actin cytoskeleton, probably by activating one or more Rho-type guanine nucleotide exchange factors. mTORC2 promotes the serum-induced formation of stress-fibers or F-actin. mTORC2 plays a critical role in AKT1 'Ser-473' phosphorylation, which may facilitate the phosphorylation of the activation loop of AKT1 on 'Thr-308' by PDK1 which is a prerequisite for full activation. mTORC2 regulates the phosphorylation of SGK1 at 'Ser-422'. mTORC2 also modulates the phosphorylation of PRKCA on 'Ser-657'. PRR5 plays an important role in regulation of PDGFRB expression and in modulation of platelet-derived growth factor signaling. May act as a tumor suppressor in breast cancer.
- Molecular Weight
- 33 kDa,50 kDa
- Gene ID
- 55615
- UniProt
- P85299
- Pathways
- PI3K-Akt Signaling
-
