PCSK4 antibody

Catalog No. ABIN7117845

Product Details anti-PCSK4 Antibody

Target: PCSK4 (Proprotein Convertase Subtilisin/kexin Type 4 (PCSK4))

Reactivity: Human, Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This PCSK4 antibody is un-conjugated

Application: Western Blotting (WB), ELISA

Purification: Immunogen affinity purified

Purity: ≥95 % as determined by SDS-PAGE

Immunogen: proprotein convertase subtilisin/kexin type 4

Isotype: IgG

Application Details

Application Notes: WB: 1:500-1:2000

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: PBS with 0.02 % sodium azide and 50 % glycerol pH 7.3,

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: -20°C for 12 months (Avoid repeated freeze / thaw cycles.)

Expiry Date: 12 months

Target Details for PCSK4

Target: PCSK4 (Proprotein Convertase Subtilisin/kexin Type 4 (PCSK4))

Alternative Name: PCSK4 (PCSK4 Products)

Synonyms: PC4 antibody, SPC5 antibody, AI647044 antibody, L21221 antibody, NEC 3 antibody, NEC3 antibody, PCSK4 antibody, pc4 antibody, spc5 antibody, MGC146505 antibody, pcsk4 antibody, proprotein convertase subtilisin/kexin type 4 antibody, proprotein convertase subtilisin/kexin type 4 L homeolog antibody, PCSK4 antibody, Pcsk4 antibody, pcsk4 antibody, pcsk4.L antibody

Background: Synonyms:PC4, PCSK4, Proprotein convertase 4, SPC5 Background:Proprotein convertase involved in the processing of hormone and other protein precursors at sites comprised of pairs of basic amino acid residues(By similarity). In males, important for ADAM2 processing as well as other acrosomal proteins with roles in fertilization and critical for normal fertilization events such as sperm capacitation, acrosome reaction and binding of sperm to zona pellucida(By similarity). Plays also a role in female fertility, involved in the regulation of trophoblast migration and placental development, may be through the proteolytical processing and activation of proteins such as IGF2(PubMed:16040806). May also participate to folliculogenesis in the ovaries(By similarity).

Molecular Weight: 54kd

Gene ID: 54760

UniProt: Q6UW60