PCSK4 antibody (AA 514-755)

Catalog No. ABIN7117845

The Rabbit Polyclonal anti-PCSK4 antibody (ABIN7117845) specifically detects PCSK4 in WB and ELISA. The antibody is reactive with Human, Mouse and Rat samples.

Quick Overview for PCSK4 antibody (AA 514-755) (ABIN7117845)

Target: PCSK4 (Proprotein Convertase Subtilisin/kexin Type 4 (PCSK4))

Reactivity: Human, Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This PCSK4 antibody is un-conjugated

Application: Western Blotting (WB), ELISA

Product Details anti-PCSK4 Antibody

Binding Specificity: AA 514-755

Purpose: PCSK4 antibody

Purification: Immunogen affinity purified

Purity: ≥95 % as determined by SDS-PAGE

Immunogen:

Immunogen sequence: 514-755aa

Immunogen: proprotein convertase subtilisin/kexin type 4

Isotype: IgG

Application Details

Application Notes: WB: 1:500-1:2000

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: PBS with 0.02 % sodium azide and 50 % glycerol pH 7.3,

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freeze / thaw cycles.

Storage: -20 °C

Storage Comment: -20°C for 12 months

Expiry Date: 12 months

Target Details for PCSK4

Target: PCSK4 (Proprotein Convertase Subtilisin/kexin Type 4 (PCSK4))

Alternative Name: PCSK4

Background:

Synonyms: Proprotein convertase subtilisin/kexin type 4|Proprotein convertase 4 (PC4)|PCSK4|PC4

Background: Proprotein convertase involved in the processing of hormone and other protein precursors at sites comprised of pairs of basic amino acid residues(By similarity). In males, important for ADAM2 processing as well as other acrosomal proteins with roles in fertilization and critical for normal fertilization events such as sperm capacitation, acrosome reaction and binding of sperm to zona pellucida(By similarity). Plays also a role in female fertility, involved in the regulation of trophoblast migration and placental development, may be through the proteolytical processing and activation of proteins such as IGF2(PubMed:16040806). May also participate to folliculogenesis in the ovaries(By similarity).

Molecular Weight: 54 kDa

Gene ID: 54760

UniProt: Q6UW60