PTGR1 antibody (AA 1-329)

Catalog No. ABIN7117867

This Rabbit Polyclonal antibody specifically detects PTGR1 in WB, ELISA and IP. It exhibits reactivity toward Human, Mouse and Rat.

Quick Overview for PTGR1 antibody (AA 1-329) (ABIN7117867)

Target: PTGR1 (Prostaglandin Reductase 1 (PTGR1))

Reactivity: Human, Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This PTGR1 antibody is un-conjugated

Application: Western Blotting (WB), ELISA, Immunoprecipitation (IP)

Product Details anti-PTGR1 Antibody

Binding Specificity: AA 1-329

Purpose: PTGR1 antibody

Purification: Immunogen affinity purified

Purity: ≥95 % as determined by SDS-PAGE

Immunogen:

Immunogen sequence: 1-329aa,full length

Immunogen: prostaglandin reductase 1

Isotype: IgG

Application Details

Application Notes: WB: 1:500-1:2000, IP: 1:200-1:2000

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: PBS with 0.02 % sodium azide and 50 % glycerol pH 7.3,

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freeze / thaw cycles.

Storage: -20 °C

Storage Comment: -20°C for 12 months

Expiry Date: 12 months

Target Details for PTGR1

Target: PTGR1 (Prostaglandin Reductase 1 (PTGR1))

Alternative Name: PTGR1

Background:

Synonyms: Prostaglandin reductase 1 (PRG-1)|15-oxoprostaglandin 13-reductase|Dithiolethione-inducible gene 1 protein (D3T-inducible gene 1 protein, DIG-1)|Leukotriene B4 12-hydroxydehydrogenase|NAD(P)H-dependent alkenal/one oxidoreductase|PTGR1|LTB4DH

Background: Functions as 15-oxo-prostaglandin 13-reductase and acts on 15-oxo-PGE1, 15-oxo-PGE2 and 15-oxo-PGE2-alpha. Has no activity towards PGE1, PGE2 and PGE2-alpha(By similarity). Catalyzes the conversion of leukotriene B4 into its biologically less active metabolite, 12-oxo-leukotriene B4. This is an initial and key step of metabolic inactivation of leukotriene B4.

Molecular Weight: 36 kDa

Gene ID: 22949

UniProt: Q14914