PDIA4 antibody

Catalog No. ABIN7117936

This Rabbit Polyclonal antibody specifically detects PDIA4 in WB, IHC, ELISA, IF and IP. It exhibits reactivity toward Human, Mouse and Rat.

Quick Overview for PDIA4 antibody (ABIN7117936)

Target: PDIA4 (Protein Disulfide Isomerase Family A, Member 4 (PDIA4))

Reactivity: Human, Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This PDIA4 antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (IHC), ELISA, Immunofluorescence (IF), Immunoprecipitation (IP)

Product Details anti-PDIA4 Antibody

Purpose: PDIA4 antibody

Purification: Immunogen affinity purified

Purity: ≥95 % as determined by SDS-PAGE

Immunogen: protein disulfide isomerase family A, member 4

Isotype: IgG

Application Details

Application Notes: WB: 1:500-1:2000, IP: 1:500-1:1000, IHC: 1:20-1:200, IF: 1:20-1:200

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: PBS with 0.02 % sodium azide and 50 % glycerol pH 7.3,

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freeze / thaw cycles.

Storage: -20 °C

Storage Comment: -20°C for 12 months

Expiry Date: 12 months

Target Details for PDIA4

Target: PDIA4 (Protein Disulfide Isomerase Family A, Member 4 (PDIA4))

Alternative Name: PDIA4

Background:

Synonyms: Protein disulfide-isomerase A4|Endoplasmic reticulum resident protein 70 (ER protein 70, ERp70)|Endoplasmic reticulum resident protein 72 (ER protein 72, ERp-72, ERp72)|PDIA4|ERP70|ERP72

Background: PDIA4(Protein disulfide-isomerase A4) is also named as ERP70, ERP72 and belongs to the protein disulfide isomerase family. It catalyzes the rearrangement of-S-S-bonds in proteins. ERp72 is a soluble protein localized in the ER lumen and contains the COOH-terminal retention signal, KEEL. There are 6 cysteine residues in the amino acid sequences of mouse and human ERp72. All of the cysteine residues occur in the internal thioredoxin motif, CGHC(PMID:15475357).

Molecular Weight: 72 kDa

UniProt: P13667

Pathways: Thyroid Hormone Synthesis, Cell RedoxHomeostasis