PPP2R2B antibody

Catalog No. ABIN7118015

The Rabbit Polyclonal anti-PPP2R2B antibody has been validated for WB, ELISA, IP and IF. It is suitable to detect PPP2R2B in samples from Human, Rat and Mouse.

Quick Overview for PPP2R2B antibody (ABIN7118015)

Target: PPP2R2B (Protein Phosphatase 2, Regulatory Subunit B, beta (PPP2R2B))

Reactivity: Human, Rat, Mouse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This PPP2R2B antibody is un-conjugated

Application: Western Blotting (WB), ELISA, Immunoprecipitation (IP), Immunofluorescence (IF)

Product Details anti-PPP2R2B Antibody

Purpose: PPP2R2B antibody

Purification: Immunogen affinity purified

Purity: ≥95 % as determined by SDS-PAGE

Immunogen: protein phosphatase 2(formerly 2A), regulatory subunit B, beta isoform

Isotype: IgG

Application Details

Application Notes: WB: 1:500-1:1000, IP: 1:500-1:1000, IF: 1:10-1:100

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: PBS with 0.02 % sodium azide and 50 % glycerol pH 7.3,

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freeze / thaw cycles.

Storage: -20 °C

Storage Comment: -20°C for 12 months

Expiry Date: 12 months

Target Details for PPP2R2B

Target: PPP2R2B (Protein Phosphatase 2, Regulatory Subunit B, beta (PPP2R2B))

Alternative Name: PPP2R2B

Background:

Synonyms: Serine/threonine-protein phosphatase 2A 55 kDa regulatory subunit B beta isoform|PP2A subunit B isoform B55-beta|PP2A subunit B isoform PR55-beta|PP2A subunit B isoform R2-beta|PP2A subunit B isoform beta|PPP2R2B

Background: The B regulatory subunit might modulate substrate selectivity and catalytic activity, and also might direct the localization of the catalytic enzyme to a particular subcellular compartment. Within the PP2A holoenzyme complex, isoform 2 is required to promote proapoptotic activity(By similarity). Isoform 2 regulates neuronal survival through the mitochondrial fission and fusion balance(By similarity).

Molecular Weight: 52 kDa

Gene ID: 5521

UniProt: Q00005

Pathways: PI3K-Akt Signaling, Mitotic G1-G1/S Phases, Hepatitis C