PTPN14 antibody

Catalog No. ABIN7118058

The Rabbit Polyclonal anti-PTPN14 antibody (ABIN7118058) specifically detects PTPN14 in WB, ELISA and IHC. The antibody is reactive with Human, Mouse and Rat samples.

Quick Overview for PTPN14 antibody (ABIN7118058)

Target: PTPN14 (Protein tyrosine Phosphatase, Non-Receptor Type 14 (PTPN14))

Reactivity: Human, Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This PTPN14 antibody is un-conjugated

Application: Western Blotting (WB), ELISA, Immunohistochemistry (IHC)

Product Details anti-PTPN14 Antibody

Purpose: PTPN14 antibody

Purification: Immunogen affinity purified

Purity: ≥95 % as determined by SDS-PAGE

Immunogen: protein tyrosine phosphatase, non-receptor type 14

Isotype: IgG

Application Details

Application Notes: WB: 1:200-1:2000, IHC: 1:20-1:200

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: PBS with 0.02 % sodium azide and 50 % glycerol pH 7.3,

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freeze / thaw cycles.

Storage: -20 °C

Storage Comment: -20°C for 12 months

Expiry Date: 12 months

Target Details for PTPN14

Target: PTPN14 (Protein tyrosine Phosphatase, Non-Receptor Type 14 (PTPN14))

Alternative Name: PTPN14

Background:

Synonyms: Tyrosine-protein phosphatase non-receptor type 14|Protein-tyrosine phosphatase pez|PTPN14|PEZ|PTPD2

Background: Protein tyrosine phosphatase which may play a role in the regulation of lymphangiogenesis, cell-cell adhesion, cell-matrix adhesion, cell migration, cell growth and also regulates TGF-beta gene expression, thereby modulating epithelial-mesenchymal transition. Mediates beta-catenin dephosphorylation at adhesion junctions. Acts as a negative regulator of the oncogenic property of YAP, a downstream target of the hippo pathway, in a cell density-dependent manner. May function as a tumor suppressor.

Molecular Weight: 150 kDa

Gene ID: 5784

UniProt: Q15678