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RAB7B antibody

RAB7B Reactivity: Human, Mouse WB, ELISA Host: Rabbit Polyclonal unconjugated
Catalog No. ABIN7118233
  • Target See all RAB7B Antibodies
    RAB7B (RAB7B, Member RAS Oncogene Family (RAB7B))
    Reactivity
    • 27
    • 1
    • 1
    Human, Mouse
    Host
    • 21
    • 6
    Rabbit
    Clonality
    • 23
    • 4
    Polyclonal
    Conjugate
    • 14
    • 3
    • 3
    • 3
    • 2
    • 2
    This RAB7B antibody is un-conjugated
    Application
    • 23
    • 22
    • 2
    • 1
    • 1
    Western Blotting (WB), ELISA
    Purification
    Immunogen affinity purified
    Purity
    ≥95 % as determined by SDS-PAGE
    Immunogen
    RAB7B, member RAS oncogene family
    Isotype
    IgG
    Top Product
    Discover our top product RAB7B Primary Antibody
  • Application Notes
    WB: 1:500-1:2000
    Restrictions
    For Research Use only
  • Format
    Liquid
    Buffer
    PBS with 0.02 % sodium azide and 50 % glycerol pH 7.3,
    Preservative
    Sodium azide
    Precaution of Use
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Storage
    -20 °C
    Storage Comment
    -20°C for 12 months (Avoid repeated freeze / thaw cycles.)
    Expiry Date
    12 months
  • Target
    RAB7B (RAB7B, Member RAS Oncogene Family (RAB7B))
    Alternative Name
    RAB7B (RAB7B Products)
    Synonyms
    RGD1562617 antibody, RAB7B antibody, RAB7 antibody, Rab7b antibody, Rab7b, member RAS oncogene family antibody, rab7B protein antibody, RAB7B, member RAS oncogene family antibody, RAB7B, member RAS oncogene family S homeolog antibody, Rab7b antibody, rab7B antibody, RAB7B antibody, rab7b.S antibody, rab7b antibody
    Background
    Synonyms:Ras-related protein Rab-7b, RAB7B Background:Controls vesicular trafficking from endosomes to the trans-Golgi network(TGN). Acts as a negative regulator of TLR9 signaling and can suppress TLR9-triggered TNFA, IL6, and IFNB production in macrophages by promoting TLR9 lysosomal degradation. Also negatively regulates TLR4 signaling in macrophages by promoting lysosomal degradation of TLR4. Promotes megakaryocytic differentiation by increasing NF-kappa-B-dependent IL6 production and subsequently enhancing the association of STAT3 with GATA1. Not involved in the regulation of the EGF-and EGFR degradation pathway.
    Molecular Weight
    23 kDa
    Gene ID
    338382
    UniProt
    Q96AH8
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