RANBP10 antibody

Catalog No. ABIN7118271

The Rabbit Polyclonal anti-RANBP10 antibody (ABIN7118271) specifically detects RANBP10 in WB, ELISA and IHC. The antibody is reactive with Human, Mouse and Rat samples.

Quick Overview for RANBP10 antibody (ABIN7118271)

Target: RANBP10 (RAN Binding Protein 10 (RANBP10))

Reactivity: Human, Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This RANBP10 antibody is un-conjugated

Application: Western Blotting (WB), ELISA, Immunohistochemistry (IHC)

Product Details anti-RANBP10 Antibody

Purpose: RANBP10 antibody

Purification: Immunogen affinity purified

Purity: ≥95 % as determined by SDS-PAGE

Immunogen: RAN binding protein 10

Isotype: IgG

Application Details

Application Notes: WB: 1:500-1:2000, IHC: 1:20-1:200

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: PBS with 0.02 % sodium azide and 50 % glycerol pH 7.3,

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freeze / thaw cycles.

Storage: -20 °C

Storage Comment: -20°C for 12 months

Expiry Date: 12 months

Target Details for RANBP10

Target: RANBP10 (RAN Binding Protein 10 (RANBP10))

Alternative Name: RANBP10

Background:

Synonyms: Ran-binding protein 10 (RanBP10)|RANBP10|KIAA1464

Background: Acts as a guanine nucleotide exchange factor(GEF) for RAN GTPase(By similarity). May play an essential role in hemostasis and in maintaining microtubule dynamics with respect to both platelet shape and function(By similarity). May act as an adapter protein to couple membrane receptors to intracellular signaling pathways. Enhances dihydrotestosterone-induced transactivation activity of AR, as well as dexamethasone-induced transactivation activity of NR3C1, but does not affect estrogen-induced transactivation. In contrast to RANBP9, does not interact with Sos and does not activate the Ras pathway.

Molecular Weight: 67-70 kDa

Gene ID: 57610

UniProt: Q6VN20