CUEDC2 antibody (AA 201-287) (HRP)

Catalog No. ABIN707540

The Rabbit Polyclonal anti-CUEDC2 antibody has been validated for ELISA, WB, IHC (p) and IHC (fro). It is suitable to detect CUEDC2 in samples from Mouse.

Quick Overview for CUEDC2 antibody (AA 201-287) (HRP) (ABIN707540)

Target: CUEDC2 (CUE Domain Containing 2 (CUEDC2))

Reactivity: Mouse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This CUEDC2 antibody is conjugated to HRP

Application: ELISA, Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunohistochemistry (Frozen Sections) (IHC (fro))

Product Details anti-CUEDC2 Antibody (HRP)

Binding Specificity: AA 201-287

Cross-Reactivity: Mouse

Predicted Reactivity: Human,Rat,Dog,Cow,Pig,Horse,Rabbit

Purification: Purified by Protein A.

Immunogen: KLH conjugated synthetic peptide derived from human CUE domain containing 2

Isotype: IgG

Application Details

Application Notes: WB 1:300-5000
IHC-P 1:200-400
IHC-F 1:100-500

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 μg/μL

Buffer: Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Handling Advice: Do NOT add Sodium Azide! Use of Sodium Azide will inhibit enzyme activity of horseradish peroxidase.

Storage: -20 °C

Storage Comment: Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.

Expiry Date: 12 months

Target Details for CUEDC2

Target: CUEDC2 (CUE Domain Containing 2 (CUEDC2))

Alternative Name: CUEDC2

Background:

Synonyms: C10orf66, bA18I14.5, CUE domain-containing protein 2, CUEDC2, HOYS6

Background: Down-regulates ESR1 protein levels through the ubiquitination-proteasome pathway, regardless of the presence of 17 beta-estradiol. Also involved in 17 beta-estradiol-induced ESR1 degradation. Controls PGR protein levels through a similar mechanism.

Gene ID: 79004

UniProt: Q9H467