ARHGAP10 antibody

Catalog No. ABIN7118479

This Rabbit Polyclonal antibody specifically detects ARHGAP10 in ELISA, WB and IHC. It exhibits reactivity toward Human and Mouse.

Quick Overview for ARHGAP10 antibody (ABIN7118479)

Target: ARHGAP10 (rho GTPase Activating Protein 10 (ARHGAP10))

Reactivity: Human, Mouse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This ARHGAP10 antibody is un-conjugated

Application: ELISA, Western Blotting (WB), Immunohistochemistry (IHC)

Product Details anti-ARHGAP10 Antibody

Purpose: ARHGAP10 antibody

Purification: Immunogen affinity purified

Purity: ≥95 % as determined by SDS-PAGE

Immunogen: Rho GTPase activating protein 10

Isotype: IgG

Application Details

Application Notes: WB: 1:500-1:2000, IHC: 1:20-1:200

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: PBS with 0.02 % sodium azide and 50 % glycerol pH 7.3,

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freeze / thaw cycles.

Storage: -20 °C

Storage Comment: -20°C for 12 months

Expiry Date: 12 months

Target Details for ARHGAP10

Target: ARHGAP10 (rho GTPase Activating Protein 10 (ARHGAP10))

Alternative Name: ARHGAP10

Background:

Synonyms: Rho GTPase-activating protein 10|GTPase regulator associated with focal adhesion kinase 2 (GRAF2)|Graf-related protein 2|Rho-type GTPase-activating protein 10|ARHGAP10|GRAF2

Background: GTPase activator for the small GTPases RhoA and Cdc42 by converting them to an inactive GDP-bound state. Essential for PTKB2 regulation of cytoskeletal organization via Rho family GTPases. Inhibits PAK2 proteolytic fragment PAK-2p34 kinase activity and changes its localization from the nucleus to the perinuclear region. Stabilizes PAK-2p34 thereby increasing stimulation of cell death(By similarity).

Molecular Weight: 89 kDa

Gene ID: 79658

UniProt: A1A4S6