Ribonuclease H1 antibody (AA 1-286)

Catalog No. ABIN7118515

This Rabbit Polyclonal antibody specifically detects Ribonuclease H1 in WB, ELISA and IP. It exhibits reactivity toward Human, Mouse and Rat.

Quick Overview for Ribonuclease H1 antibody (AA 1-286) (ABIN7118515)

Target: Ribonuclease H1 (RNASEH1)

Reactivity: Human, Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This Ribonuclease H1 antibody is un-conjugated

Application: Western Blotting (WB), ELISA, Immunoprecipitation (IP)

Product Details anti-Ribonuclease H1 Antibody

Binding Specificity: AA 1-286

Purpose: RNASEH1 antibody

Purification: Immunogen affinity purified

Purity: ≥95 % as determined by SDS-PAGE

Immunogen:

Immunogen sequence: 1-286aa, full length

Immunogen: ribonuclease H1

Isotype: IgG

Application Details

Application Notes: WB: 1:500-1:2000, IP: 1:200-1:2000

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: PBS with 0.02 % sodium azide and 50 % glycerol pH 7.3,

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freeze / thaw cycles.

Storage: -20 °C

Storage Comment: -20°C for 12 months

Expiry Date: 12 months

Target Details for Ribonuclease H1

Target: Ribonuclease H1 (RNASEH1)

Alternative Name: RNASEH1

Background:

Synonyms: Ribonuclease H1 (RNase H1)|Ribonuclease H type II|RNASEH1|RNH1

Background: Endonuclease that specifically degrades the RNA of RNA-DNA hybrids(PubMed:10497183). Plays a role in RNA polymerase II(RNAp II) transcription termination by degrading R-loop RNA-DNA hybrid formation at G-rich pause sites located downstream of the poly(A) site and behind the elongating RNAp II(PubMed:21700224).

Molecular Weight: 32 kDa

Gene ID: 246243

UniProt: O60930