RNF2 antibody

Catalog No. ABIN7118645

The Rabbit Polyclonal anti-RNF2 antibody has been validated for WB, ELISA, IHC and IP. It is suitable to detect RNF2 in samples from Human, Mouse and Rat.

Quick Overview for RNF2 antibody (ABIN7118645)

Target: RNF2 (Ring Finger Protein 2 (RNF2))

Reactivity: Human, Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This RNF2 antibody is un-conjugated

Application: Western Blotting (WB), ELISA, Immunohistochemistry (IHC), Immunoprecipitation (IP)

Product Details anti-RNF2 Antibody

Purpose: RNF2 antibody

Purification: Immunogen affinity purified

Purity: ≥95 % as determined by SDS-PAGE

Immunogen: ring finger protein 2

Isotype: IgG

Application Details

Application Notes: WB: 1:500 - 1:2000, IHC: 1:50 - 1:200, IP: 1:50 - 1:200

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: PBS with 0.02 % sodium azide and 50 % glycerol pH 7.3,

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freeze / thaw cycles.

Storage: -20 °C

Storage Comment: -20°C for 12 months

Expiry Date: 12 months

Target Details for RNF2

Target: RNF2 (Ring Finger Protein 2 (RNF2))

Alternative Name: RNF2

Background:

Synonyms: E3 ubiquitin-protein ligase RING2|Huntingtin-interacting protein 2-interacting protein 3 (HIP2-interacting protein 3)|Protein DinG|RING finger protein 1B (RING1b)|RING finger protein 2|RING finger protein BAP-1|RING-type E3 ubiquitin transferase RING2|RNF2|BAP1|DING|HIPI3|RING1B

Background: Polycomb group (PcG) of proteins form the multiprotein complexes that are important for the transcription repression of various genes involved in development and cell proliferation. The protein encoded by this gene is one of the PcG proteins. It has been shown to interact with, and suppress the activity of, transcription factor CP2 (TFCP2/CP2). Studies of the mouse counterpart suggested the involvement of this gene in the specification of anterior-posterior axis, as well as in cell proliferation in early development. This protein was also found to interact with huntingtin interacting protein 2 (HIP2), an ubiquitin-conjugating enzyme, and possess ubiquitin ligase activity.

Molecular Weight: 39 kDa

Gene ID: 6045

UniProt: Q99496