SEC13 antibody

Catalog No. ABIN7118814

The Rabbit Polyclonal anti-SEC13 antibody (ABIN7118814) specifically detects SEC13 in WB, ELISA, IHC, IP and IF. The antibody is reactive with Human, Mouse and Rat samples.

Quick Overview for SEC13 antibody (ABIN7118814)

Target: SEC13 (SEC13 Homolog (SEC13))

Reactivity: Human, Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This SEC13 antibody is un-conjugated

Application: Western Blotting (WB), ELISA, Immunohistochemistry (IHC), Immunoprecipitation (IP), Immunofluorescence (IF)

Product Details anti-SEC13 Antibody

Purpose: SEC13 antibody

Purification: Immunogen affinity purified

Purity: ≥95 % as determined by SDS-PAGE

Immunogen: SEC13 homolog

Isotype: IgG

Application Details

Application Notes: WB: 1:500-1:2000, IP: 1:200-1:1000, IHC: 1:20-1:200, IF: 1:20-1:200

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: PBS with 0.02 % sodium azide and 50 % glycerol pH 7.3,

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freeze / thaw cycles.

Storage: -20 °C

Storage Comment: -20°C for 12 months

Expiry Date: 12 months

Target Details for SEC13

Target: SEC13 (SEC13 Homolog (SEC13))

Alternative Name: SEC13

Background:

Synonyms: Protein SEC13 homolog|GATOR2 complex protein SEC13|SEC13-like protein 1|SEC13-related protein|SEC13|D3S1231E|SEC13A|SEC13L1|SEC13R

Background: Functions as a component of the nuclear pore complex(NPC) and the COPII coat. At the endoplasmic reticulum, SEC13 is involved in the biogenesis of COPII-coated vesicles. As a component of the GATOR subcomplex GATOR2, functions as an activator of the amino acid-sensing branch of the TORC1 pathway. Inhibits the GATOR1 subcomplex, an inhibitor of the amino acid-sensing branch of the TORC1 pathway(PubMed:23723238). Functions downstream and is regulated by amino acid sensors like SESN2(Probable).

Molecular Weight: 36 kDa

Gene ID: 6396

UniProt: P55735