STK4 antibody

Catalog No. ABIN7118929

This Rabbit Polyclonal antibody specifically detects STK4 in WB, ELISA, IHC and IP. It exhibits reactivity toward Human, Mouse and Rat.

Quick Overview for STK4 antibody (ABIN7118929)

Target: STK4 (serine/threonine Kinase 4 (STK4))

Reactivity: Human, Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This STK4 antibody is un-conjugated

Application: Western Blotting (WB), ELISA, Immunohistochemistry (IHC), Immunoprecipitation (IP)

Product Details anti-STK4 Antibody

Purpose: STK4 antibody

Purification: Immunogen affinity purified

Purity: ≥95 % as determined by SDS-PAGE

Immunogen: serine/threonine kinase 4

Isotype: IgG

Application Details

Application Notes: WB: 1:500 - 1:2000, IHC: 1:50 - 1:200, IP : 1:20 - 1:50

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: PBS with 0.02 % sodium azide and 50 % glycerol pH 7.3,

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freeze / thaw cycles.

Storage: -20 °C

Storage Comment: -20°C for 12 months

Expiry Date: 12 months

Target Details for STK4

Target: STK4 (serine/threonine Kinase 4 (STK4))

Alternative Name: STK4

Background:

Synonyms: Serine/threonine-protein kinase 4|Mammalian STE20-like protein kinase 1 (MST-1)|STE20-like kinase MST1|Serine/threonine-protein kinase Krs-2|Serine/threonine-protein kinase 4 37kDa subunit (MST1/N)|Serine/threonine-protein kinase 4 18kDa subunit (MST1/C)|STK4|KRS2|MST1

Background: The protein encoded by this gene is a cytoplasmic kinase that is structurally similar to the yeast Ste20p kinase, which acts upstream of the stress-induced mitogen-activated protein kinase cascade. The encoded protein can phosphorylate myelin basic protein and undergoes autophosphorylation. A caspase-cleaved fragment of the encoded protein has been shown to be capable of phosphorylating histone H2B. The particular phosphorylation catalyzed by this protein has been correlated with apoptosis, and it's possible that this protein induces the chromatin condensation observed in this process.

Molecular Weight: 56 kDa

Gene ID: 6789

UniProt: Q13043

Pathways: Tube Formation