SLC4A8 antibody

Catalog No. ABIN7119311

The Rabbit Polyclonal anti-SLC4A8 antibody is suitable to detect SLC4A8 in samples from Human, Mouse and Rat. It has been validated for ELISA and WB.

Quick Overview for SLC4A8 antibody (ABIN7119311)

Target: SLC4A8 (Solute Carrier Family 4, Sodium Bicarbonate Cotransporter, Member 8 (SLC4A8))

Reactivity: Human, Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This SLC4A8 antibody is un-conjugated

Application: ELISA, Western Blotting (WB)

Product Details anti-SLC4A8 Antibody

Purpose: Slc4a8 antibody

Purification: Immunogen affinity purified

Purity: ≥95 % as determined by SDS-PAGE

Immunogen: solute carrier family 4, sodium bicarbonate cotransporter, member 8

Isotype: IgG

Application Details

Application Notes: WB: 1:500-1:2000

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: PBS with 0.02 % sodium azide and 50 % glycerol pH 7.3,

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freeze / thaw cycles.

Storage: -20 °C

Storage Comment: -20°C for 12 months

Expiry Date: 12 months

Target Details for SLC4A8

Target: SLC4A8 (Solute Carrier Family 4, Sodium Bicarbonate Cotransporter, Member 8 (SLC4A8))

Alternative Name: Slc4a8

Background:

Synonyms: Electroneutral sodium bicarbonate exchanger 1|Electroneutral Na+-driven Cl-HCO3 exchanger|Solute carrier family 4 member 8|k-NBC3|Slc4a8|Ndcbe1

Background: Mediates electroneutral sodium-and carbonate-dependent chloride-HCO3(-) exchange with a Na(+):HCO3(-) stoichiometry of 2:1. Plays a major role in pH regulation in neurons. May be involved in cell pH regulation by transporting HCO3(-) from blood to cell. Enhanced expression in severe acid stress could be important for cell survival by mediating the influx of HCO3(-) into the cells. Also mediates lithium-dependent HCO3(-) cotransport. May be regulated by osmolarity(By similarity).

Molecular Weight: 121 kDa

Gene ID: 315311

UniProt: Q6RVG2