SLC4A8 antibody (N-Term)
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- Target See all SLC4A8 Antibodies
- SLC4A8 (Solute Carrier Family 4, Sodium Bicarbonate Cotransporter, Member 8 (SLC4A8))
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Binding Specificity
- N-Term
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Reactivity
- Human
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Host
- Rabbit
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Clonality
- Polyclonal
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Conjugate
- This SLC4A8 antibody is un-conjugated
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Application
- Western Blotting (WB)
- Cross-Reactivity
- Mouse (Murine), Rat (Rattus)
- Cross-Reactivity (Details)
- Mouse (93 %), Rat (92 %)
- Characteristics
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Rabbit Polyclonal antibody to SLC4A8 (solute carrier family 4, sodium bicarbonate cotransporter, member 8)
SLC4A8 antibody [N1N2], N-term - Purification
- Purified by antigen-affinity chromatography.
- Immunogen
- Recombinant protein encompassing a sequence within the N-terminus region of human SLC4A8. The exact sequence is proprietary.
- Isotype
- IgG
- Top Product
- Discover our top product SLC4A8 Primary Antibody
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- Application Notes
- Suggested dilution Reference Western blot 1:500-1:3000* Not tested in other applications. *Optimal dilutions/concentrations should be determined by the researcher.Suggested dilutionReferenceWestern blot1:500-1:3000*
- Comment
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Positive Control: IMR32 , U87-MG
- Restrictions
- For Research Use only
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- Format
- Liquid
- Concentration
- 0.99 mg/mL
- Buffer
- 0.1M Tris, 0.1M Glycine, 20 % Glycerol ( pH 7). 0.01 % Thimerosal was added as a preservative.
- Preservative
- Thimerosal (Merthiolate)
- Precaution of Use
- This product contains Thimerosal (Merthiolate): a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Storage
- -20 °C
- Storage Comment
- Keep as concentrated solution. Aliquot and store at -20°C or below. Avoid multiple freeze-thaw cycles.
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- Target
- SLC4A8 (Solute Carrier Family 4, Sodium Bicarbonate Cotransporter, Member 8 (SLC4A8))
- Alternative Name
- SLC4A8 (SLC4A8 Products)
- Synonyms
- SLC4A8 antibody, AW493845 antibody, C230026C11 antibody, NDCBE antibody, kNBC-3 antibody, NBC3 antibody, KNBC3 antibody, solute carrier family 4, sodium bicarbonate cotransporter, member 8 S homeolog antibody, solute carrier family 4 member 8 antibody, solute carrier family 4, sodium bicarbonate cotransporter, member 8 antibody, solute carrier family 4 (anion exchanger), member 8 antibody, slc4a8.S antibody, SLC4A8 antibody, slc4a8 antibody, Slc4a8 antibody
- Background
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Mediates electroneutral sodium- and carbonate-dependent choride-HCO3(-) exchange with a Na(+):HCO3(-) stoichiometry of 2:1. Plays a major role in pH regulation in neurons. May be involved in cell pH regulation by transporting HCO3(-) from blood to cell. Enhanced expression in severe acid stress could be important for cell survival by mediating the influx of HCO3(-) into the cells. Also mediates lithium-dependent HCO3(-) cotransport. May be regulated by osmolarity.
Cellular Localization: Membrane, Multi-pass membrane protein - Molecular Weight
- 123 kDa
- Gene ID
- 9498
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