SOS1 antibody

Catalog No. ABIN7119340

This Rabbit Polyclonal antibody specifically detects SOS1 in WB, ELISA and IF. It exhibits reactivity toward Human, Mouse and Rat.

Quick Overview for SOS1 antibody (ABIN7119340)

Target: SOS1 (Son of Sevenless Homolog 1 (SOS1))

Reactivity: Human, Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This SOS1 antibody is un-conjugated

Application: Western Blotting (WB), ELISA, Immunofluorescence (IF)

Product Details anti-SOS1 Antibody

Purpose: SOS1 antibody

Purification: Immunogen affinity purified

Purity: ≥95 % as determined by SDS-PAGE

Immunogen: son of sevenless homolog 1

Isotype: IgG

Application Details

Application Notes: WB: 1:500 - 1:2000, IF: 1:50 - 1:100

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: PBS with 0.02 % sodium azide and 50 % glycerol pH 7.3,

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freeze / thaw cycles.

Storage: -20 °C

Storage Comment: -20°C for 12 months

Expiry Date: 12 months

Target Details for SOS1

Target: SOS1 (Son of Sevenless Homolog 1 (SOS1))

Alternative Name: SOS1

Background:

Synonyms: Son of sevenless homolog 1 (SOS-1)|SOS1

Background: Promotes the exchange of Ras-bound GDP by GTP(PubMed:8493579). Probably by promoting Ras activation, regulates phosphorylation of MAP kinase MAPK3 in response to EGF(PubMed:17339331). Catalytic component of a trimeric complex that participates in transduction of signals from Ras to Rac by promoting the Rac-specific guanine nucleotide exchange factor(GEF) activity(By similarity).

Molecular Weight: 180 kDa

Gene ID: 6654

UniProt: Q07889

Pathways: RTK Signaling, TCR Signaling, Fc-epsilon Receptor Signaling Pathway, EGFR Signaling Pathway, Neurotrophin Signaling Pathway, Hepatitis C, Signaling Events mediated by VEGFR1 and VEGFR2, Signaling of Hepatocyte Growth Factor Receptor, BCR Signaling