STOML2 antibody

Catalog No. ABIN7119538

This Mouse Monoclonal antibody specifically detects STOML2 in WB, IHC, ELISA and IP. It exhibits reactivity toward Human, Mouse and Rat.

Quick Overview for STOML2 antibody (ABIN7119538)

Target: STOML2 (Stomatin (EPB72)-Like 2 (STOML2))

Reactivity: Human, Mouse, Rat

Host: Mouse

Clonality: Monoclonal

Conjugate: This STOML2 antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (IHC), ELISA, Immunoprecipitation (IP)

Clone: 5D10

Product Details anti-STOML2 Antibody

Purpose: STOML2 antibody

Purification: Protein A+G purification

Purity: ≥95 % as determined by SDS-PAGE

Immunogen: stomatin(EPB72)-like 2

Isotype: IgG2a

Application Details

Application Notes: WB: 1:2000-1:10000, IP: 1:500-1:1000, IHC: 1:50-1:500

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: PBS with 0.02 % sodium azide and 50 % glycerol pH 7.3,

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freeze / thaw cycles.

Storage: -20 °C

Storage Comment: -20°C for 12 months

Expiry Date: 12 months

Target Details for STOML2

Target: STOML2 (Stomatin (EPB72)-Like 2 (STOML2))

Alternative Name: STOML2

Background:

Synonyms: Stomatin-like protein 2, mitochondrial (SLP-2)|EPB72-like protein 2|Paraprotein target 7 (Paratarg-7)|STOML2|SLP2

Background: Mitochondrial protein that probably regulates the biogenesis and the activity of mitochondria. Stimulates cardiolipin biosynthesis, binds cardiolipin-enriched membranes where it recruits and stabilizes some proteins including prohibitin and may therefore act in the organization of functional microdomains in mitochondrial membranes. Through regulation of the mitochondrial function may play a role into several biological processes including cell migration, cell proliferation, T-cell activation, calcium homeostasis and cellular response to stress. May play a role in calcium homeostasis through negative regulation of calcium efflux from mitochondria. Required for mitochondrial hyperfusion a pro-survival cellular response to stress which results in increased ATP production by mitochondria. May also regulate the organization of functional domains at the plasma membrane and play a role in T-cell activation through association with the T-cell receptor signaling complex and its regulation.

Molecular Weight: 39 kDa

Gene ID: 30968

UniProt: Q9UJZ1

Pathways: SARS-CoV-2 Protein Interactome, The Global Phosphorylation Landscape of SARS-CoV-2 Infection