STXBP2 antibody

Catalog No. ABIN7119716

The Rabbit Polyclonal anti-STXBP2 antibody is suitable to detect STXBP2 in samples from Human, Mouse and Rat. It has been validated for WB, ELISA and IHC.

Quick Overview for STXBP2 antibody (ABIN7119716)

Target: STXBP2 (Syntaxin Binding Protein 2 (STXBP2))

Reactivity: Human, Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This STXBP2 antibody is un-conjugated

Application: Western Blotting (WB), ELISA, Immunohistochemistry (IHC)

Product Details anti-STXBP2 Antibody

Purpose: STXBP2 antibody

Purification: Immunogen affinity purified

Purity: ≥95 % as determined by SDS-PAGE

Immunogen: syntaxin binding protein 2

Isotype: IgG

Application Details

Application Notes: WB: 1:500 - 1:2000, IHC: 1:50 - 1:200

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: PBS with 0.02 % sodium azide and 50 % glycerol pH 7.3,

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freeze / thaw cycles.

Storage: -20 °C

Storage Comment: -20°C for 12 months

Expiry Date: 12 months

Target Details for STXBP2

Target: STXBP2 (Syntaxin Binding Protein 2 (STXBP2))

Alternative Name: STXBP2

Background:

Synonyms: Syntaxin-binding protein 2|Protein unc-18 homolog 2 (Unc18-2)|Protein unc-18 homolog B (Unc-18B)|STXBP2|UNC18B

Background: This gene encodes a member of the STXBP/unc-18/SEC1 family. The encoded protein is involved in intracellular trafficking, control of SNARE (soluble NSF attachment protein receptor) complex assembly, and the release of cytotoxic granules by natural killer cells. Mutations in this gene are associated with familial hemophagocytic lymphohistiocytosis. Alternatively spliced transcript variants encoding different isoforms have been noted for this gene.

Molecular Weight: 66 kDa

Gene ID: 6813

UniProt: Q15833

Pathways: Regulation of Leukocyte Mediated Immunity, Positive Regulation of Immune Effector Process, Synaptic Vesicle Exocytosis