TAO Kinase 3 antibody

Catalog No. ABIN7119771

This anti-TAO Kinase 3 antibody is a Rabbit Polyclonal antibody detecting TAO Kinase 3 in WB, ELISA, IHC and IP. Suitable for Human, Mouse and Rat.

Quick Overview for TAO Kinase 3 antibody (ABIN7119771)

Target: TAO Kinase 3 (TAOK3)

Reactivity: Human, Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This TAO Kinase 3 antibody is un-conjugated

Application: Western Blotting (WB), ELISA, Immunohistochemistry (IHC), Immunoprecipitation (IP)

Product Details anti-TAO Kinase 3 Antibody

Purpose: TAOK3 antibody

Purification: Immunogen affinity purified

Purity: ≥95 % as determined by SDS-PAGE

Immunogen: TAO kinase 3

Isotype: IgG

Application Details

Application Notes: WB: 1:500-1:2000, IP: 1:200-1:1000, IHC: 1:20-1:200

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: PBS with 0.02 % sodium azide and 50 % glycerol pH 7.3,

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freeze / thaw cycles.

Storage: -20 °C

Storage Comment: -20°C for 12 months

Expiry Date: 12 months

Target Details for TAO Kinase 3

Target: TAO Kinase 3 (TAOK3)

Alternative Name: TAOK3

Background:

Synonyms: Serine/threonine-protein kinase TAO3|Cutaneous T-cell lymphoma-associated antigen HD-CL-09 (CTCL-associated antigen HD-CL-09)|Dendritic cell-derived protein kinase|JNK/SAPK-inhibitory kinase|Jun kinase-inhibitory kinase|Kinase from chicken homolog A (hKFC-A)|Thousand and one amino acid protein 3|TAOK3|DPK|JIK|KDS|MAP3K18

Background: Serine/threonine-protein kinase that acts as a regulator of the p38/MAPK14 stress-activated MAPK cascade and of the MAPK8/JNK cascade. Acts as an activator of the p38/MAPK14 stress-activated MAPK cascade. In response to DNA damage, involved in the G2/M transition DNA damage checkpoint by activating the p38/MAPK14 stress-activated MAPK cascade, probably by mediating phosphorylation of upstream MAP2K3 and MAP2K6 kinases. Inhibits basal activity of MAPK8/JNK cascade and diminishes its activation in response epidermal growth factor(EGF).

Molecular Weight: 100-105 kDa

Gene ID: 51347

UniProt: Q9H2K8