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TELO2 antibody

TELO2 Reactivity: Human WB, ELISA, IHC, IF, IP Host: Mouse Monoclonal 8B6 unconjugated
Catalog No. ABIN7119825
  • Target See all TELO2 Antibodies
    TELO2 (TEL2, Telomere Maintenance 2, Homolog (TELO2))
    Reactivity
    • 20
    • 3
    • 3
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Human
    Host
    • 20
    Mouse
    Clonality
    • 20
    Monoclonal
    Conjugate
    • 10
    • 2
    • 2
    • 2
    • 2
    • 2
    This TELO2 antibody is un-conjugated
    Application
    • 20
    • 15
    • 14
    • 13
    • 2
    • 2
    • 1
    • 1
    Western Blotting (WB), ELISA, Immunohistochemistry (IHC), Immunofluorescence (IF), Immunoprecipitation (IP)
    Purification
    Protein A+G purification
    Purity
    ≥95 % as determined by SDS-PAGE
    Immunogen
    TEL2, telomere maintenance 2, homolog(S. cerevisiae)
    Clone
    8B6
    Isotype
    IgG2a
    Top Product
    Discover our top product TELO2 Primary Antibody
  • Application Notes
    WB: 1:1000-1:4000, IP: 1:500-1:1000, IHC: 1:20-1:200, IF: 1:10-1:100
    Restrictions
    For Research Use only
  • Format
    Liquid
    Buffer
    PBS with 0.02 % sodium azide and 50 % glycerol pH 7.3,
    Preservative
    Sodium azide
    Precaution of Use
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Storage
    -20 °C
    Storage Comment
    -20°C for 12 months (Avoid repeated freeze / thaw cycles.)
    Expiry Date
    12 months
  • Target
    TELO2 (TEL2, Telomere Maintenance 2, Homolog (TELO2))
    Alternative Name
    TELO2 (TELO2 Products)
    Synonyms
    RGD1305553 antibody, 1200003M09Rik antibody, AI415602 antibody, Tel2 antibody, mKIAA0683 antibody, CLK2 antibody, TEL2 antibody, telomere maintenance 2 antibody, Telo2 antibody, TELO2 antibody
    Background
    Synonyms:KIAA0683 Background:Regulator of the DNA damage response(DDR). Part of the TTT complex that is required to stabilize protein levels of the phosphatidylinositol 3-kinase-related protein kinase(PIKK) family proteins. The TTT complex is involved in the cellular resistance to DNA damage stresses, like ionizing radiation(IR), ultraviolet(UV) and mitomycin C(MMC). Together with the TTT complex and HSP90 may participate in the proper folding of newly synthesized PIKKs. Promotes assembly, stabilizes and maintains the activity of mTORC1 and mTORC2 complexes, which regulate cell growth and survival in response to nutrient and hormonal signals. May be involved in telomere length regulation.
    Molecular Weight
    92 kDa
    Gene ID
    9894
    UniProt
    Q9Y4R8
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