TRIP13 antibody (AA 1-200)

Catalog No. ABIN7119956

The Rabbit Polyclonal anti-TRIP13 antibody has been validated for WB, ELISA, IHC and IP. It is suitable to detect TRIP13 in samples from Human, Mouse and Rat.

Quick Overview for TRIP13 antibody (AA 1-200) (ABIN7119956)

Target: TRIP13 (Thyroid Hormone Receptor Interactor 13 (TRIP13))

Reactivity: Human, Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This TRIP13 antibody is un-conjugated

Application: Western Blotting (WB), ELISA, Immunohistochemistry (IHC), Immunoprecipitation (IP)

Product Details anti-TRIP13 Antibody

Binding Specificity: AA 1-200

Purpose: TRIP13 antibody

Purification: Immunogen affinity purified

Purity: ≥95 % as determined by SDS-PAGE

Immunogen:

Immunogen sequence: 1-200aa

Immunogen: thyroid hormone receptor interactor 13

Isotype: IgG

Application Details

Application Notes: WB: 1:500-1:2000, IP: 1:200-1:1000, IHC: 1:50-1:500

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: PBS with 0.02 % sodium azide and 50 % glycerol pH 7.3,

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freeze / thaw cycles.

Storage: -20 °C

Storage Comment: -20°C for 12 months

Expiry Date: 12 months

Target Details for TRIP13

Target: TRIP13 (Thyroid Hormone Receptor Interactor 13 (TRIP13))

Alternative Name: TRIP13

Background:

Synonyms: Pachytene checkpoint protein 2 homolog|Human papillomavirus type 16 E1 protein-binding protein (16E1-BP, HPV16 E1 protein-binding protein)|Thyroid hormone receptor interactor 13|Thyroid receptor-interacting protein 13 (TR-interacting protein 13, TRIP-13)|TRIP13|PCH2

Background: Plays a key role in chromosome recombination and chromosome structure development during meiosis. Required at early steps in meiotic recombination that leads to non-crossovers pathways. Also needed for efficient completion of homologous synapsis by influencing crossover distribution along the chromosomes affecting both crossovers and non-crossovers pathways. Also required for development of higher-order chromosome structures and is needed for synaptonemal-complex formation. In males, required for efficient synapsis of the sex chromosomes and for sex body formation. Promotes early steps of the DNA double-strand breaks(DSBs) repair process upstream of the assembly of RAD51 complexes. Required for depletion of HORMAD1 and HORMAD2 from synapsed chromosomes(By similarity).

Molecular Weight: 49 kDa

Gene ID: 9319

UniProt: Q15645