TLR7 antibody (AA 861-1049)

Catalog No. ABIN7120008

This anti-TLR7 antibody is a Rabbit Polyclonal antibody detecting TLR7 in WB, ELISA and IHC. Suitable for Human, Mouse and Rat.

Quick Overview for TLR7 antibody (AA 861-1049) (ABIN7120008)

Target: TLR7 (Toll-Like Receptor 7 (TLR7))

Reactivity: Human, Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This TLR7 antibody is un-conjugated

Application: Western Blotting (WB), ELISA, Immunohistochemistry (IHC)

Product Details anti-TLR7 Antibody

Binding Specificity: AA 861-1049

Purpose: TLR7 antibody

Purification: Immunogen affinity purified

Purity: ≥95 % as determined by SDS-PAGE

Immunogen:

Immunogen sequence: 861-1049aa

Immunogen: toll-like receptor 7

Isotype: IgG

Application Details

Application Notes: WB: 1:200-1:600, IHC: 1:20-1:200

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: PBS with 0.02 % sodium azide and 50 % glycerol pH 7.3,

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freeze / thaw cycles.

Storage: -20 °C

Storage Comment: -20°C for 12 months

Expiry Date: 12 months

Target Details for TLR7

Target: TLR7 (Toll-Like Receptor 7 (TLR7))

Alternative Name: TLR7

Background:

Synonyms: Toll-like receptor 7|TLR7

Background: Key component of innate and adaptive immunity. TLRs(Toll-like receptors) control host immune response against pathogens through recognition of molecular patterns specific to microorganisms. TLR7 is a nucleotide-sensing TLR which is activated by single-stranded RNA. Acts via MYD88 and TRAF6, leading to NF-kappa-B activation, cytokine secretion and the inflammatory response(By similarity).

Molecular Weight: 121 kDa

Gene ID: 51284

UniProt: Q9NYK1

Pathways: TLR Signaling, Activation of Innate immune Response, Toll-Like Receptors Cascades