TCF4 antibody (AA 399-503)

Catalog No. ABIN7120057

This Rabbit Polyclonal antibody specifically detects TCF4 in WB and ELISA. It exhibits reactivity toward Human and Rat.

Quick Overview for TCF4 antibody (AA 399-503) (ABIN7120057)

Target: TCF4 (Transcription Factor 4 (TCF4))

Reactivity: Human, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This TCF4 antibody is un-conjugated

Application: Western Blotting (WB), ELISA

Product Details anti-TCF4 Antibody

Binding Specificity: AA 399-503

Purpose: TCF4 antibody

Purification: Immunogen affinity purified

Purity: ≥95 % as determined by SDS-PAGE

Immunogen:

Immunogen sequence: 399-503aa

Immunogen: transcription factor 4

Isotype: IgG

Application Details

Application Notes: WB: 1:500-1:1000

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: PBS with 0.02 % sodium azide and 50 % glycerol pH 7.3,

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freeze / thaw cycles.

Storage: -20 °C

Storage Comment: -20°C for 12 months

Expiry Date: 12 months

Target Details for TCF4

Target: TCF4 (Transcription Factor 4 (TCF4))

Alternative Name: TCF4

Background:

Synonyms: Transcription factor 4 (TCF-4)|Class B basic helix-loop-helix protein 19 (bHLHb19)|Immunoglobulin transcription factor 2 (ITF-2)|SL3-3 enhancer factor 2 (SEF-2)|TCF4|BHLHB19|ITF2|SEF2

Background: Transcription factor that binds to the immunoglobulin enchancer Mu-E5/KE5-motif. Involved in the initiation of neuronal differentiation. Activates transcription by binding to the E box(5'-CANNTG-3'). Binds to the E-box present in the somatostatin receptor 2 initiator element(SSTR2-INR) to activate transcription(By similarity). Preferentially binds to either 5'-ACANNTGT-3' or 5'-CCANNTGG-3'.

Molecular Weight: 48-70 kDa

UniProt: P15884

Pathways: WNT Signaling, Positive Regulation of Peptide Hormone Secretion, Peptide Hormone Metabolism, Regulation of Hormone Metabolic Process, Carbohydrate Homeostasis, Stem Cell Maintenance, Protein targeting to Nucleus