TCF7L2 antibody
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- Target See all TCF7L2 Antibodies
- TCF7L2 (Transcription Factor 7-Like 2 (T-Cell Specific, HMG-Box) (TCF7L2))
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Reactivity
- Human, Mouse, Rat
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Host
- Rabbit
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Clonality
- Polyclonal
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Conjugate
- This TCF7L2 antibody is un-conjugated
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Application
- Western Blotting (WB), ELISA, Immunoprecipitation (IP)
- Purification
- Immunogen affinity purified
- Purity
- ≥95 % as determined by SDS-PAGE
- Immunogen
- transcription factor 7-like 2(T-cell specific, HMG-box)
- Isotype
- IgG
- Top Product
- Discover our top product TCF7L2 Primary Antibody
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anti-Transcription Factor 7-Like 2 (T-Cell Specific, HMG-Box) (TCF7L2) (AA 490-596) antibody
TCF7L2 Reactivity: Human WB, ELISA, IHC (p), IF Host: Mouse Monoclonal 3A4 unconjugated
anti-Transcription Factor 7-Like 2 (T-Cell Specific, HMG-Box) (TCF7L2) (AA 1-455) antibodyTCF7L2 Reactivity: Human WB, ELISA, RNAi Host: Mouse Monoclonal 1B1 unconjugated
anti-Transcription Factor 7-Like 2 (T-Cell Specific, HMG-Box) (TCF7L2) (N-Term) antibodyTCF7L2 Reactivity: Human, Mouse, Rat WB, ELISA, IHC (p), IHC Host: Rabbit Polyclonal unconjugated
anti-Transcription Factor 7-Like 2 (T-Cell Specific, HMG-Box) (TCF7L2) (AA 490-596) antibodyTCF7L2 Reactivity: Human WB, ELISA, IF Host: Mouse Monoclonal 1A1 unconjugated
anti-Transcription Factor 7-Like 2 (T-Cell Specific, HMG-Box) (TCF7L2) (AA 61-90), (N-Term) antibodyTCF7L2 Reactivity: Human, Mouse WB Host: Rabbit Polyclonal RB19650 unconjugated
anti-Transcription Factor 7-Like 2 (T-Cell Specific, HMG-Box) (TCF7L2) (AA 1-455) antibodyTCF7L2 Reactivity: Human WB, ELISA, IHC (p) Host: Mouse Monoclonal 1A9 unconjugated
anti-Transcription Factor 7-Like 2 (T-Cell Specific, HMG-Box) (TCF7L2) (Middle Region) antibodyTCF7L2 Reactivity: Human, Mouse, Rat, Cow, Zebrafish (Danio rerio), Guinea Pig, Horse, Rabbit, Dog WB Host: Rabbit Polyclonal unconjugated
anti-Transcription Factor 7-Like 2 (T-Cell Specific, HMG-Box) (TCF7L2) (AA 401-550) antibodyTCF7L2 Reactivity: Rat ELISA, IF (cc), IF (p), IHC (p), IHC (fro) Host: Rabbit Polyclonal unconjugated
anti-Transcription Factor 7-Like 2 (T-Cell Specific, HMG-Box) (TCF7L2) (AA 490-596) antibodyTCF7L2 Reactivity: Human WB, ELISA Host: Mouse Polyclonal unconjugated
anti-Transcription Factor 7-Like 2 (T-Cell Specific, HMG-Box) (TCF7L2) (AA 1-100) antibodyTCF7L2 Reactivity: Human WB Host: Rabbit Polyclonal unconjugated
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- Application Notes
- WB: 1:500-1:2000, IP: 1:200-1:2000
- Restrictions
- For Research Use only
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- Format
- Liquid
- Buffer
- PBS with 0.02 % sodium azide and 50 % glycerol pH 7.3,
- Preservative
- Sodium azide
- Precaution of Use
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Storage
- -20 °C
- Storage Comment
- -20°C for 12 months (Avoid repeated freeze / thaw cycles.)
- Expiry Date
- 12 months
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- Target
- TCF7L2 (Transcription Factor 7-Like 2 (T-Cell Specific, HMG-Box) (TCF7L2))
- Alternative Name
- TCF7L2 (TCF7L2 Products)
- Background
- Synonyms:TCF4 Background:Participates in the Wnt signaling pathway and modulates MYC expression by binding to its promoter in a sequence-specific manner. Acts as repressor in the absence of CTNNB1, and as activator in its presence. Activates transcription from promoters with several copies of the Tcf motif 5'-CCTTTGATC-3' in the presence of CTNNB1. TLE1, TLE2, TLE3 and TLE4 repress transactivation mediated by TCF7L2/TCF4 and CTNNB1. Expression of dominant-negative mutants results in cell-cycle arrest in G1. Necessary for the maintenance of the epithelial stem-cell compartment of the small intestine.
- Molecular Weight
- 68 kDa
- Gene ID
- 6934
- UniProt
- Q9NQB0
- Pathways
- WNT Signaling, Positive Regulation of Peptide Hormone Secretion, Peptide Hormone Metabolism, Regulation of Hormone Metabolic Process, Carbohydrate Homeostasis, Stem Cell Maintenance, Protein targeting to Nucleus
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