TFB2M antibody
Quick Overview for TFB2M antibody (ABIN7120070)
Target
See all TFB2M AntibodiesReactivity
Host
Clonality
Conjugate
Application
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Purpose
- TFB2M antibody
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Purification
- Immunogen affinity purified
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Purity
- ≥95 % as determined by SDS-PAGE
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Immunogen
- transcription factor B2, mitochondrial
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Isotype
- IgG
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anti-Transcription Factor B2, Mitochondrial (TFB2M) (AA 297-396) antibody
TFB2M Reactivity: Human ELISA, WB Host: Mouse Monoclonal 2E10 unconjugated
anti-Transcription Factor B2, Mitochondrial (TFB2M) (AA 368-396), (C-Term) antibodyTFB2M Reactivity: Human WB, IHC (p) Host: Rabbit Polyclonal RB22408 unconjugated
anti-Transcription Factor B2, Mitochondrial (TFB2M) (AA 297-396) antibodyTFB2M Reactivity: Human ELISA, WB Host: Mouse Polyclonal unconjugated
anti-Transcription Factor B2, Mitochondrial (TFB2M) (AA 1-396) antibodyTFB2M Reactivity: Human WB Host: Mouse Polyclonal unconjugated
anti-Transcription Factor B2, Mitochondrial (TFB2M) (Internal Region) antibodyVerified TFB2M Reactivity: Human ELISA, WB, IHC Host: Goat Polyclonal unconjugated
anti-Transcription Factor B2, Mitochondrial (TFB2M) (AA 101-150) antibodyTFB2M Reactivity: Human, Rat, Horse WB, IHC, IHC (p) Host: Rabbit Polyclonal unconjugated
anti-Transcription Factor B2, Mitochondrial (TFB2M) (AA 30-108) antibodyTFB2M Reactivity: Human ELISA, IHC Host: Rabbit Polyclonal unconjugated
anti-Transcription Factor B2, Mitochondrial (TFB2M) (Internal Region) antibodyVerified TFB2M Reactivity: Rat, Mouse ELISA, WB Host: Goat Polyclonal unconjugated
anti-Transcription Factor B2, Mitochondrial (TFB2M) (C-Term) antibodyVerified TFB2M Reactivity: Human ELISA, IHC Host: Goat Polyclonal unconjugated
anti-Transcription Factor B2, Mitochondrial (TFB2M) (N-Term) antibodyTFB2M Reactivity: Human, Rat, Horse, Rabbit WB, IHC Host: Rabbit Polyclonal unconjugated
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Application Notes
- WB: 1:500-1:2000
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Restrictions
- For Research Use only
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Format
- Liquid
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Buffer
- PBS with 0.02 % sodium azide and 50 % glycerol pH 7.3,
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Preservative
- Sodium azide
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Precaution of Use
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Handling Advice
- Avoid repeated freeze / thaw cycles.
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Storage
- -20 °C
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Storage Comment
- -20°C for 12 months
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Expiry Date
- 12 months
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- TFB2M (Transcription Factor B2, Mitochondrial (TFB2M))
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Alternative Name
- TFB2M
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Background
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Synonyms: Dimethyladenosine transferase 2, mitochondrial|Hepatitis C virus NS5A-transactivated protein 5 (HCV NS5A-transactivated protein 5)|Mitochondrial 12S rRNA dimethylase 2|Mitochondrial transcription factor B2 (h-mtTFB, h-mtTFB2, hTFB2M, mtTFB2)|S-adenosylmethionine-6-N', N'-adenosyl(rRNA) dimethyltransferase 2|TFB2M|NS5ATP5
Background: S-adenosyl-L-methionine-dependent methyltransferase which specifically dimethylates mitochondrial 12S rRNA at the conserved stem loop. Also required for basal transcription of mitochondrial DNA, probably via its interaction with POLRMT and TFAM. Stimulates transcription independently of the methyltransferase activity. Compared to TFB1M, it activates transcription of mitochondrial DNA more efficiently, while it has less methyltransferase activity.
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Molecular Weight
- 45-50 kDa
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Gene ID
- 64216
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UniProt
- Q9H5Q4
Target
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