Transferrin Receptor antibody
Quick Overview for Transferrin Receptor antibody (ABIN7120098)
Target
See all Transferrin Receptor (TFRC) AntibodiesReactivity
Host
Clonality
Conjugate
Application
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Purpose
- TFRC antibody
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Purification
- Immunogen affinity purified
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Purity
- ≥95 % as determined by SDS-PAGE
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Immunogen
- transferrin receptor(p90, CD71)
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Isotype
- IgG
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Application Notes
- WB: 1:500-1:5000, IP: 1:200-1:2000, IHC: 1:100-1:400, IF: 1:50-1:500
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Restrictions
- For Research Use only
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Format
- Liquid
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Buffer
- PBS with 0.02 % sodium azide and 50 % glycerol pH 7.3,
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Preservative
- Sodium azide
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Precaution of Use
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Handling Advice
- Avoid repeated freeze / thaw cycles.
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Storage
- -20 °C
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Storage Comment
- -20°C for 12 months
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Expiry Date
- 12 months
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- Transferrin Receptor (TFRC) (Transferrin Receptor (p90, CD71) (TFRC))
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Alternative Name
- TFRC
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Background
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Synonyms: Transferrin receptor protein 1 (TR, TfR, TfR1, Trfr)|T9|p90|Transferrin receptor protein 1, serum form (sTfR)|TFRC|CD71
Background: CD71, also known as transferrin receptor protein 1(TfR1), is a transmembrane glycoprotein composed of two disulfide-linked monomers, each of 90 kDa molecular weight. Each monomer binds one holo-transferrin molecule creating an iron-Tf-TfR complex which enters the cell by endocytosis. CD71 is present on actively proliferating cells and is essential for iron transport into proliferating cells.
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Molecular Weight
- 90 kDa
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Gene ID
- 7018
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UniProt
- P02786
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Pathways
- Transition Metal Ion Homeostasis
Target
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