TRIM32 antibody

Catalog No. ABIN7120284

The Rabbit Polyclonal anti-TRIM32 antibody (ABIN7120284) specifically detects TRIM32 in WB, IHC, ELISA and IF. The antibody is reactive with Human, Mouse and Rat samples.

Quick Overview for TRIM32 antibody (ABIN7120284)

Target: TRIM32 (Tripartite Motif Containing 32 (TRIM32))

Reactivity: Human, Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This TRIM32 antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (IHC), ELISA, Immunofluorescence (IF)

Product Details anti-TRIM32 Antibody

Purpose: TRIM32 antibody

Purification: Immunogen affinity purified

Purity: ≥95 % as determined by SDS-PAGE

Immunogen: tripartite motif-containing 32

Isotype: IgG

Application Details

Application Notes: WB: 1:200-1:2000, IHC: 1:20-1:200, IF: 1:20-1:200

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: PBS with 0.02 % sodium azide and 50 % glycerol pH 7.3,

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freeze / thaw cycles.

Storage: -20 °C

Storage Comment: -20°C for 12 months

Expiry Date: 12 months

Target Details for TRIM32

Target: TRIM32 (Tripartite Motif Containing 32 (TRIM32))

Alternative Name: TRIM32

Background:

Synonyms: E3 ubiquitin-protein ligase TRIM32|72 kDa Tat-interacting protein|RING-type E3 ubiquitin transferase TRIM32|Tripartite motif-containing protein 32|Zinc finger protein HT2A|TRIM32|HT2A

Background: Has an E3 ubiquitin ligase activity. Ubiquitinates DTNBP1(dysbindin) and promotes its degradation. May ubiquitinate BBS2. May play a significant role in mediating the biological activity of the HIV-1 Tat protein in vivo. Binds specifically to the activation domain of HIV-1 Tat and can also interact with the HIV-2 and EIAV Tat proteins in vivo.

Molecular Weight: 65-72 kDa

Gene ID: 22954

UniProt: Q13049

Pathways: Negative Regulation of intrinsic apoptotic Signaling