TRMT5 antibody

Catalog No. ABIN7120311

The Rabbit Polyclonal anti-TRMT5 antibody (ABIN7120311) specifically detects TRMT5 in WB and ELISA. The antibody is reactive with Human, Rat and Mouse samples.

Quick Overview for TRMT5 antibody (ABIN7120311)

Target: TRMT5 (tRNA Methyltransferase 5 (TRMT5))

Reactivity: Human, Rat, Mouse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This TRMT5 antibody is un-conjugated

Application: Western Blotting (WB), ELISA

Product Details anti-TRMT5 Antibody

Purpose: TRMT5 antibody

Purification: Immunogen affinity purified

Purity: ≥95 % as determined by SDS-PAGE

Immunogen: TRM5 tRNA methyltransferase 5 homolog

Isotype: IgG

Application Details

Application Notes: WB: 1:500-1:5000

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: PBS with 0.02 % sodium azide and 50 % glycerol pH 7.3,

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freeze / thaw cycles.

Storage: -20 °C

Storage Comment: -20°C for 12 months

Expiry Date: 12 months

Target Details for TRMT5

Target: TRMT5 (tRNA Methyltransferase 5 (TRMT5))

Alternative Name: TRMT5

Background:

Synonyms: tRNA (guanine(37)-N1)-methyltransferase|M1G-methyltransferase|tRNA [GM37] methyltransferase|tRNA methyltransferase 5 homolog|TRMT5|KIAA1393|TRM5

Background: Involved in mitochondrial tRNA methylation(PubMed:26189817). Specifically methylates the N1 position of guanosine-37 in various tRNAs. Methylation is not dependent on the nature of the nucleoside 5' of the target nucleoside. This is the first step in the biosynthesis of wybutosine(yW), a modified base adjacent to the anticodon of tRNAs and required for accurate decoding.

Molecular Weight: 58 kDa

Gene ID: 57570

UniProt: Q32P41