TPM3
Reactivity: Human
WB
Host: Rabbit
Polyclonal
RB54537
unconjugated
Application Notes
WB: 1:500 - 1:2000, IHC: 1:50 - 1:200
Restrictions
For Research Use only
Format
Liquid
Buffer
PBS with 0.02 % sodium azide and 50 % glycerol pH 7.3 ,
Preservative
Sodium azide
Precaution of Use
This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Storage
-20 °C
Storage Comment
-20°C for 12 months (Avoid repeated freeze / thaw cycles.)
Expiry Date
12 months
Target
TPM3
(Tropomyosin 3 (TPM3))
Alternative Name
TPM3
Background
Synonyms:CAPM1, CFTD, HEL-189, HEL-S-82p, hscp30,NEM1, OK/SW-cl.5, TM-5,TM3, TM30, TM30nm, TM5, TPMsk3, TRK Background:This gene encodes a member of the tropomyosin family of actin-binding proteins. Tropomyosins are dimers of coiled-coil proteins that provide stability to actin filaments and regulate access of other actin-binding proteins. Mutations in this gene result in autosomal dominant nemaline myopathy and other muscle disorders. This locus is involved in translocations with other loci, including anaplastic lymphoma receptor tyrosine kinase (ALK) and neurotrophic tyrosine kinase receptor type 1 (NTRK1), which result in the formation of fusion proteins that act as oncogenes. There are numerous pseudogenes for this gene on different chromosomes. Alternative splicing results in multiple transcript variants.