TWSG1 antibody

Catalog No. ABIN7120434

Product Details anti-TWSG1 Antibody

Target: TWSG1 (Twisted Gastrulation Homolog 1 (TWSG1))

Reactivity: Human, Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This TWSG1 antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (IHC), ELISA

Purification: Immunogen affinity purified

Purity: ≥95 % as determined by SDS-PAGE

Immunogen: twisted gastrulation homolog 1

Isotype: IgG

Application Details

Application Notes: WB: 1:200-1:1000, IHC: 1:20-1:200

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: PBS with 0.02 % sodium azide and 50 % glycerol pH 7.3,

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: -20°C for 12 months (Avoid repeated freeze / thaw cycles.)

Expiry Date: 12 months

Target Details for TWSG1

Target: TWSG1 (Twisted Gastrulation Homolog 1 (TWSG1))

Alternative Name: TWSG1 (TWSG1 Products)

Synonyms: TWSG1 antibody, TSG antibody, DKFZp469J051 antibody, 1810013J15Rik antibody, 9030422N06Rik antibody, AW552143 antibody, D17Ertd403e antibody, Tsg antibody, Twg antibody, fi23f01 antibody, tsg antibody, tsga antibody, twsg1 antibody, wu:fi23f01 antibody, twsg antibody, tsg1 antibody, tsgb antibody, ztsg1 antibody, twisted gastrulation BMP signaling modulator 1 antibody, twisted gastrulation homolog 1 (Drosophila) antibody, twisted gastrulation BMP signaling modulator 1a antibody, twisted gastrulation BMP signaling modulator 1 S homeolog antibody, twisted gastrulation BMP signaling modulator 1 L homeolog antibody, twisted gastrulation BMP signaling modulator 1b antibody, TWSG1 antibody, Twsg1 antibody, twsg1a antibody, twsg1.S antibody, twsg1.L antibody, twsg1b antibody

Background: Synonyms:TSG, TWSG1 Background:May be involved in dorsoventral axis formation. Seems to antagonize BMP signaling by forming ternary complexes with CHRD and BMPs, thereby preventing BMPs from binding to their receptors. In addition to the anti-BMP function, also has pro-BMP activity, partly mediated by cleavage and degradation of CHRD, which releases BMPs from ternary complexes. May be an important modulator of BMP-regulated cartilage development and chondrocyte differentiation. May play a role in thymocyte development(By similarity).

Molecular Weight: 35 kDa

Gene ID: 57045

UniProt: Q9GZX9