USP49 antibody

Catalog No. ABIN7120526

Product Details anti-USP49 Antibody

Target: USP49 (Ubiquitin Specific Peptidase 49 (USP49))

Reactivity: Human, Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This USP49 antibody is un-conjugated

Application: Western Blotting (WB), ELISA, Immunohistochemistry (IHC)

Purification: Immunogen affinity purified

Purity: ≥95 % as determined by SDS-PAGE

Immunogen: ubiquitin specific peptidase 49

Isotype: IgG

Application Details

Application Notes: WB: 1:500-1:5000, IHC: 1:20-1:200

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: PBS with 0.02 % sodium azide and 50 % glycerol pH 7.3,

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: -20°C for 12 months (Avoid repeated freeze / thaw cycles.)

Expiry Date: 12 months

Target Details for USP49

Target: USP49 (Ubiquitin Specific Peptidase 49 (USP49))

Alternative Name: USP49 (USP49 Products)

Synonyms: USP49 antibody, C330046L10Rik antibody, Gm545 antibody, ubiquitin specific peptidase 49 antibody, USP49 antibody, Usp49 antibody

Background: Synonyms:Deubiquitinating enzyme 49, Ubiquitin thiolesterase 49, USP49 Background:Specifically deubiquitinates histone H2B at 'Lys-120'(H2BK120Ub). H2BK120Ub is a specific tag for epigenetic transcriptional activation and acts as a regulator of mRNA splicing. Deubiquitination is required for efficient cotranscriptional splicing of a large set of exons.

Molecular Weight: 73 kDa

Gene ID: 25862

UniProt: Q70CQ1