B3GNT5 antibody

Catalog No. ABIN7120596

The Rabbit Polyclonal anti-B3GNT5 antibody (ABIN7120596) specifically detects B3GNT5 in ELISA, WB and IHC. The antibody is reactive with Human, Mouse and Rat samples.

Quick Overview for B3GNT5 antibody (ABIN7120596)

Target: B3GNT5 (UDP-GlcNAc:betaGal beta-1,3-N-Acetylglucosaminyltransferase 5 (B3GNT5))

Reactivity: Human, Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This B3GNT5 antibody is un-conjugated

Application: ELISA, Western Blotting (WB), Immunohistochemistry (IHC)

Product Details anti-B3GNT5 Antibody

Purpose: B3GNT5 antibody

Purification: Immunogen affinity purified

Purity: ≥95 % as determined by SDS-PAGE

Immunogen: UDP-GlcNAc:betaGal beta-1,3-N-acetylglucosaminyltransferase 5

Isotype: IgG

Application Details

Application Notes: WB: 1:500-1:2000, IHC: 1:20-1:200

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: PBS with 0.02 % sodium azide and 50 % glycerol pH 7.3,

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freeze / thaw cycles.

Storage: -20 °C

Storage Comment: -20°C for 12 months

Expiry Date: 12 months

Target Details for B3GNT5

Target: B3GNT5 (UDP-GlcNAc:betaGal beta-1,3-N-Acetylglucosaminyltransferase 5 (B3GNT5))

Alternative Name: B3GNT5

Background:

Synonyms: Lactosylceramide 1,3-N-acetyl-beta-D-glucosaminyltransferase|Lactotriaosylceramide synthase (Lc(3)Cer synthase, Lc3 synthase)|UDP-GlcNAc:beta-Gal beta-1,3-N-acetylglucosaminyltransferase 5 (BGnT-5, Beta-1,3-Gn-T5, Beta-1,3-N-acetylglucosaminyltransferase 5, Beta3Gn-T5)|B3GNT5

Background: Beta-1,3-N-acetylglucosaminyltransferase that plays a key role in the synthesis of lacto-or neolacto-series carbohydrate chains on glycolipids, notably by participating in biosynthesis of HNK-1 and Lewis X carbohydrate structures. Has strong activity toward lactosylceramide(LacCer) and neolactotetraosylceramide(nLc(4)Cer, paragloboside), resulting in the synthesis of Lc(3)Cer and neolactopentaosylceramide(nLc(5)Cer), respectively. Probably plays a central role in regulating neolacto-series glycolipid synthesis during embryonic development.

Molecular Weight: 44 kDa

Gene ID: 84002

UniProt: Q9BYG0