VPS8 antibody

Catalog No. ABIN7120719

The Rabbit Polyclonal anti-VPS8 antibody (ABIN7120719) specifically detects VPS8 in WB, ELISA, IF and IP. The antibody is reactive with Human, Mouse and Rat samples.

Quick Overview for VPS8 antibody (ABIN7120719)

Target: VPS8 (Vacuolar Protein Sorting 8 Homolog (VPS8))

Reactivity: Human, Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This VPS8 antibody is un-conjugated

Application: Western Blotting (WB), ELISA, Immunofluorescence (IF), Immunoprecipitation (IP)

Product Details anti-VPS8 Antibody

Purpose: VPS8 antibody

Purification: Immunogen affinity purified

Purity: ≥95 % as determined by SDS-PAGE

Immunogen: vacuolar protein sorting 8 homolog

Isotype: IgG

Application Details

Application Notes: WB: 1:500-1:5000,IP: 1:200-1:2000, IF: 1:10-1:100

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: PBS with 0.02 % sodium azide and 50 % glycerol pH 7.3,

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freeze / thaw cycles.

Storage: -20 °C

Storage Comment: -20°C for 12 months

Expiry Date: 12 months

Target Details for VPS8

Target: VPS8 (Vacuolar Protein Sorting 8 Homolog (VPS8))

Alternative Name: VPS8

Background:

Synonyms: Vacuolar protein sorting-associated protein 8 homolog|VPS8|KIAA0804

Background: Plays a role in vesicle-mediated protein trafficking of the endocytic membrane transport pathway. Believed to act as a component of the putative CORVET endosomal tethering complexes which is proposed to be involved in the Rab5-to-Rab7 endosome conversion probably implicating MON1A/B, and via binding SNAREs and SNARE complexes to mediate tethering and docking events during SNARE-mediated membrane fusion. The CORVET complex is proposed to function as a Rab5 effector to mediate early endosome fusion probably in specific endosome subpopulations(PubMed:25266290). Functions predominantly in APPL1-containing endosomes(PubMed:25266290).

Molecular Weight: 151 kDa

Gene ID: 23355

UniProt: Q8N3P4