VPS33B antibody

Catalog No. ABIN7120722

The Rabbit Polyclonal anti-VPS33B antibody (ABIN7120722) specifically detects VPS33B in ELISA, WB, IHC and IF. The antibody is reactive with Human, Mouse, Rat and Zebrafish (Danio rerio) samples.

Quick Overview for VPS33B antibody (ABIN7120722)

Target: VPS33B (Vacuolar Protein Sorting-Associated Protein 33B (VPS33B))

Reactivity: Human, Mouse, Rat, Zebrafish (Danio rerio)

Host: Rabbit

Clonality: Polyclonal

Conjugate: This VPS33B antibody is un-conjugated

Application: ELISA, Western Blotting (WB), Immunohistochemistry (IHC), Immunofluorescence (IF)

Product Details anti-VPS33B Antibody

Purpose: VPS33B antibody

Purification: Immunogen affinity purified

Purity: ≥95 % as determined by SDS-PAGE

Immunogen: vacuolar protein sorting 33 homolog B(yeast)

Isotype: IgG

Application Details

Application Notes: WB: 1:500-1:2000, IHC: 1:50-1:200, IF: 1:10-1:100

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: PBS with 0.02 % sodium azide and 50 % glycerol pH 7.3,

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freeze / thaw cycles.

Storage: -20 °C

Storage Comment: -20°C for 12 months

Expiry Date: 12 months

Target Details for VPS33B

Target: VPS33B (Vacuolar Protein Sorting-Associated Protein 33B (VPS33B))

Alternative Name: VPS33B

Background:

Synonyms: Vacuolar protein sorting-associated protein 33B (hVPS33B)|VPS33B

Background: May play a role in vesicle-mediated protein trafficking to lysosomal compartments and in membrane docking/fusion reactions of late endosomes/lysosomes. Mediates phagolysosomal fusion in macrophages(PubMed:18474358). Proposed to be involved in endosomal maturation implicating VIPAS39. In epithelial cells, the VPS33B:VIPAS39 complex may play a role in the apical recycling pathway and in the maintenance of the apical-basolateral polarity(PubMed:20190753). Seems to be involved in the sorting of specific cargos from the trans-Golgi network to alpha-granule-destined multivesicular bodies(MVBs) promoting MVBs maturation in megakaryocytes(By similarity).

Molecular Weight: 71 kDa

Gene ID: 26276

UniProt: Q9H267