The Rabbit Polyclonal anti-VPS25 antibody has been validated for WB, ELISA and IHC. It is suitable to detect VPS25 in samples from Human, Mouse and Rat.
VPS25
Reactivity: Human
IHC
Polyclonal
unconjugated
Application Notes
WB: 1:500-1:2000, IHC: 1:20-1:200
Restrictions
For Research Use only
Format
Liquid
Buffer
PBS with 0.02 % sodium azide and 50 % glycerol pH 7.3,
Preservative
Sodium azide
Precaution of Use
This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Storage
-20 °C
Storage Comment
-20°C for 12 months (Avoid repeated freeze / thaw cycles.)
Expiry Date
12 months
Target
VPS25
(Vacuolar Protein-Sorting-Associated Protein 25 (VPS25))
Alternative Name
VPS25
Background
Synonyms:DERP9, EAP20, ESCRT II complex subunit VPS25, FAP20, hVps25, VPS25 Background:Component of the ESCRT-II complex(endosomal sorting complex required for transport II), which is required for multivesicular body(MVB) formation and sorting of endosomal cargo proteins into MVBs. The MVB pathway mediates delivery of transmembrane proteins into the lumen of the lysosome for degradation. The ESCRT-II complex is probably involved in the recruitment of the ESCRT-III complex. The ESCRT-II complex may also play a role in transcription regulation, possibly via its interaction with ELL. The ESCRT-II complex may be involved in facilitating the budding of certain RNA viruses.