VPS25 antibody

Catalog No. ABIN7120724

The Rabbit Polyclonal anti-VPS25 antibody has been validated for WB, ELISA and IHC. It is suitable to detect VPS25 in samples from Human, Mouse and Rat.

Quick Overview for VPS25 antibody (ABIN7120724)

Target: VPS25 (Vacuolar Protein-Sorting-Associated Protein 25 (VPS25))

Reactivity: Human, Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This VPS25 antibody is un-conjugated

Application: Western Blotting (WB), ELISA, Immunohistochemistry (IHC)

Product Details anti-VPS25 Antibody

Purpose: VPS25 antibody

Purification: Immunogen affinity purified

Purity: ≥95 % as determined by SDS-PAGE

Immunogen: vacuolar protein sorting 25 homolog

Isotype: IgG

Application Details

Application Notes: WB: 1:500-1:2000, IHC: 1:20-1:200

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: PBS with 0.02 % sodium azide and 50 % glycerol pH 7.3,

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freeze / thaw cycles.

Storage: -20 °C

Storage Comment: -20°C for 12 months

Expiry Date: 12 months

Target Details for VPS25

Target: VPS25 (Vacuolar Protein-Sorting-Associated Protein 25 (VPS25))

Alternative Name: VPS25

Background:

Synonyms: Vacuolar protein-sorting-associated protein 25 (hVps25)|Dermal papilla-derived protein 9|ELL-associated protein of 20 kDa|ESCRT-II complex subunit VPS25|VPS25|DERP9|EAP20

Background: Component of the ESCRT-II complex(endosomal sorting complex required for transport II), which is required for multivesicular body(MVB) formation and sorting of endosomal cargo proteins into MVBs. The MVB pathway mediates delivery of transmembrane proteins into the lumen of the lysosome for degradation. The ESCRT-II complex is probably involved in the recruitment of the ESCRT-III complex. The ESCRT-II complex may also play a role in transcription regulation, possibly via its interaction with ELL. The ESCRT-II complex may be involved in facilitating the budding of certain RNA viruses.

Molecular Weight: 21 kDa

Gene ID: 84313

UniProt: Q9BRG1