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WWP1 antibody

WWP1 Reactivity: Human, Mouse, Rat ELISA, IF, IHC, IP, WB Host: Rabbit Polyclonal unconjugated
Catalog No. ABIN7120866
$413.85
Plus shipping costs $45.00
100 μg
Shipping to: United States
Delivery in 10 to 13 Business Days
  • Target See all WWP1 Antibodies
    WWP1 (WW Domain Containing E3 Ubiquitin Protein Ligase 1 (WWP1))
    Reactivity
    • 25
    • 5
    • 3
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    Human, Mouse, Rat
    Host
    • 20
    • 6
    Rabbit
    Clonality
    • 21
    • 5
    Polyclonal
    Conjugate
    • 19
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This WWP1 antibody is un-conjugated
    Application
    • 17
    • 9
    • 4
    • 4
    • 4
    • 2
    • 1
    • 1
    • 1
    • 1
    ELISA, Immunofluorescence (IF), Immunohistochemistry (IHC), Immunoprecipitation (IP), Western Blotting (WB)
    Purification
    Immunogen affinity purified
    Purity
    ≥95 % as determined by SDS-PAGE
    Immunogen
    WW domain containing E3 ubiquitin protein ligase 1
    Isotype
    IgG
  • Application Notes
    WB: 1:200-1:2000, IP: 1:200-1:1000, IF: 1:20-1:200
    Restrictions
    For Research Use only
  • Format
    Liquid
    Buffer
    PBS with 0.02 % sodium azide and 50 % glycerol pH 7.3,
    Precaution of Use
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Storage
    -20 °C
    Storage Comment
    -20°C for 12 months (Avoid repeated freeze / thaw cycles.)
    Expiry Date
    12 months
  • Target
    WWP1 (WW Domain Containing E3 Ubiquitin Protein Ligase 1 (WWP1))
    Alternative Name
    WWP1 (WWP1 Products)
    Synonyms
    AIP5 antibody, Tiul1 antibody, hSDRP1 antibody, 8030445B08Rik antibody, SDRP1 antibody, WWP1 antibody, aip5 antibody, tiul1 antibody, hsdrp1 antibody, WW domain containing E3 ubiquitin protein ligase 1 antibody, WWP1 antibody, Wwp1 antibody, wwp1 antibody
    Background
    Synonyms: AIP5, DKFZp434D2111, hSDRP1, Tiul1, WW domain containing protein 1, WWP1
    E3 ubiquitin-protein ligase which accepts ubiquitin from an E2 ubiquitin-conjugating enzyme in the form of a thioester and then directly transfers the ubiquitin to targeted substrates. Ubiquitinates ERBB4 isoforms JM-A CYT-1 and JM-B CYT-1, KLF2, KLF5 and TP63 and promotes their proteasomal degradation. Ubiquitinates RNF11 without targeting it for degradation. Ubiquitinates and promotes degradation of TGFBR1, the ubiquitination is enhanced by SMAD7. Ubiquitinates SMAD6 and SMAD7. Ubiquitinates and promotes degradation of SMAD2 in response to TGF-beta signaling, which requires interaction with TGIF.
    Molecular Weight
    95 kDa
    Gene ID
    11059
    UniProt
    Q9H0M0
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