YTHDC2 antibody (AA 1131-1430)
Quick Overview for YTHDC2 antibody (AA 1131-1430) (ABIN7120902)
Target
Reactivity
Host
Clonality
Conjugate
Application
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Binding Specificity
- AA 1131-1430
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Purpose
- YTHDC2 antibody
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Purification
- Immunogen affinity purified
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Purity
- ≥95 % as determined by SDS-PAGE
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Immunogen
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Immunogen sequence: 1131-1430aa
Immunogen: 3'-5' RNA helicase YTHDC2
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Isotype
- IgG
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anti-YTH Domain Containing 2 (YTHDC2) (AA 1131-1430) antibody
YTHDC2 Reactivity: Human WB Host: Rabbit Polyclonal unconjugated
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Application Notes
- WB: 1:500-1:2000, IF: 1:50-1:200
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Restrictions
- For Research Use only
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Format
- Liquid
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Buffer
- PBS with 0.02 % sodium azide and 50 % glycerol pH 7.3,
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Preservative
- Sodium azide
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Precaution of Use
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Handling Advice
- Avoid repeated freeze / thaw cycles.
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Storage
- -20 °C
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Storage Comment
- -20°C for 12 months
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Expiry Date
- 12 months
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- YTHDC2 (YTH Domain Containing 2 (YTHDC2))
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Alternative Name
- YTHDC2
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Background
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Synonyms: 3'-5' RNA helicase YTHDC2|YTH domain-containing protein 2 (hYTHDC2)|YTHDC2
Background: This gene encodes a member of the DEAH (Asp-Glu-Ala-His) subfamily of proteins, part of the DEAD (Asp-Glu-Ala-Asp) box family of RNA helicases. The encoded protein binds to N6-methyladenosine, a common modified RNA nucleotide that is enriched in the stop codons and 3' UTRs of eukaryotic messenger RNAs. Binding of proteins to this modified nucleotide may regulate mRNA translation and stability. This gene may be associated with susceptibility to pancreatic cancer in human patients, and knockdown of this gene resulted in reduced proliferation in a human liver cancer cell line.
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Molecular Weight
- 160 kDa
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Gene ID
- 64848
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UniProt
- Q9H6S0
Target
-
