HOMER2 antibody (AA 301-354) (HRP)

Catalog No. ABIN707795

The Rabbit Polyclonal anti-HOMER2 antibody has been validated for ELISA, WB, IHC (fro) and IHC (p). It is suitable to detect HOMER2 in samples from Rat.

Quick Overview for HOMER2 antibody (AA 301-354) (HRP) (ABIN707795)

Target: HOMER2 (Homer Homolog 2 (HOMER2))

Reactivity: Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This HOMER2 antibody is conjugated to HRP

Application: ELISA, Western Blotting (WB), Immunohistochemistry (Frozen Sections) (IHC (fro)), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Product Details anti-HOMER2 Antibody (HRP)

Binding Specificity: AA 301-354

Cross-Reactivity: Rat

Predicted Reactivity: Human,Mouse,Cow,Pig,Rabbit

Purification: Purified by Protein A.

Immunogen: KLH conjugated synthetic peptide derived from human HOMER2

Isotype: IgG

Application Details

Application Notes: WB 1:300-5000
IHC-P 1:200-400
IHC-F 1:100-500

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 μg/μL

Buffer: Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Handling Advice: Do NOT add Sodium Azide! Use of Sodium Azide will inhibit enzyme activity of horseradish peroxidase.

Storage: -20 °C

Storage Comment: Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.

Expiry Date: 12 months

Target Details for HOMER2

Target: HOMER2 (Homer Homolog 2 (HOMER2))

Alternative Name: HOMER2

Background:

Synonyms: Cupidin, HOME2_HUMAN, HOMER 2, HOMER 2A, HOMER 2B, Homer homolog 2 Drosophila, Homer homolog 3, Homer neuronal immediate early gene 2, Homer protein homolog 2, Homer-2, Homer2, HOMER2A, HOMER2B, Vesl 2, Vesl2.

Background: Postsynaptic density scaffolding protein. Binds and cross-links cytoplasmic regions of GRM1, GRM5, ITPR1, DNM3, RYR1, RYR2, SHANK1 and SHANK3. By physically linking GRM1 and GRM5 with ER-associated ITPR1 receptors, it aids the coupling of surface receptors to intracellular calcium release. May also couple GRM1 to PI3 kinase through its interaction with AGAP2. Isoforms can be differently regulated and may play an important role in maintaining the plasticity at glutamatergic synapses.

Gene ID: 9455

UniProt: Q9NSB8

Pathways: Synaptic Membrane, Regulation of G-Protein Coupled Receptor Protein Signaling