ZKSCAN3 antibody

Catalog No. ABIN7120976

The Rabbit Polyclonal anti-ZKSCAN3 antibody is suitable to detect ZKSCAN3 in samples from Human and Mouse. It has been validated for ELISA and WB.

Quick Overview for ZKSCAN3 antibody (ABIN7120976)

Target: ZKSCAN3 (Zinc Finger Protein 306 (ZKSCAN3))

Reactivity: Human, Mouse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This ZKSCAN3 antibody is un-conjugated

Application: ELISA, Western Blotting (WB)

Product Details anti-ZKSCAN3 Antibody

Purpose: ZKSCAN3 antibody

Purification: Immunogen affinity purified

Purity: ≥95 % as determined by SDS-PAGE

Immunogen: zinc finger with KRAB and SCAN domains 3

Isotype: IgG

Application Details

Application Notes: WB: 1:500-1:5000

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: PBS with 0.02 % sodium azide and 50 % glycerol pH 7.3,

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freeze / thaw cycles.

Storage: -20 °C

Storage Comment: -20°C for 12 months

Expiry Date: 12 months

Target Details for ZKSCAN3

Target: ZKSCAN3 (Zinc Finger Protein 306 (ZKSCAN3))

Alternative Name: ZKSCAN3

Background:

Synonyms: Zinc finger protein with KRAB and SCAN domains 3|Zinc finger and SCAN domain-containing protein 13|Zinc finger protein 306|Zinc finger protein 309|Zinc finger protein 47 homolog (Zf47, Zfp-47)|ZKSCAN3|ZFP47|ZNF306|ZNF309|ZSCAN13

Background: Transcriptional factor that binds to the consensus sequence 5'-[GT][AG][AGT]GGGG-3' and acts as a repressor of autophagy. Specifically represses expression of genes involved in autophagy and lysosome biogenesis/function such as MAP1LC3B, ULK1 or WIPI2. Associates with chromatin at the ITGB4 and VEGF promoters. Also acts as a transcription activator and promotes cancer cell progression and/or migation in various tumors and myelomas.

Molecular Weight: 62 kDa

Gene ID: 80317

UniProt: Q9BRR0