TOM1L1 antibody

Catalog No. ABIN7504136

This Mouse Monoclonal antibody specifically detects TOM1L1 in IHC (f). It exhibits reactivity toward Human.

Quick Overview for TOM1L1 antibody (ABIN7504136)

Target: TOM1L1 (Target of Myb1 (Chicken)-Like 1 (TOM1L1))

Reactivity: Human

Host: Mouse

Clonality: Monoclonal

Conjugate: This TOM1L1 antibody is un-conjugated

Application: Immunohistochemistry (Formalin-fixed Sections) (IHC (f))

Product Details anti-TOM1L1 Antibody

Specificity: Tom1 (target of Myb 1) is a 492 amino acid cytoplasmic protein that belongs to the Tom1 family. Widely expressed with highest expression in heart, liver, placenta and skeletal muscle, Tom1 is thought to be involved in intracellular trafficking and may be associated with the translocation of ubiquitinated proteins to early endosomes for degradation. Tom1 contains one GAT domain and one VHS domain through which it interacts and complexes with proteins such as Tollip and endofin (also known as SARA). These interactions recruit Tom1 to the endosome, allowing it to participate in the endosomal trafficking of ubiquitin-tagged proteins.

Cross-Reactivity (Details): Human.

Purification: 200ug/ml of Ab purified from Bioreactor Concentrate by Protein A/G.

Immunogen: Recombinant full-length human TOM1L1 protein

Isotype: IgG

Application Details

Application Notes:

Positive Control: Human kidney.

Known Application: Immunohistochemistry (Formalin-fixed) (1-2 μg/mL for 30 minutes at RT)(Staining of formalin-fixed tissues requires heating tissue sections in 10 mM Tris with 1 mM EDTA, pH 9.0, for 45 min at 95 °C followed by cooling at RT for 20 minutes)Optimal dilution for a specific application should be determined.

Restrictions: For Research Use only

Handling

Concentration: 200 μg/mL

Buffer: Prepared in 10 mM PBS with 0.05 % BSA and 0.05 % azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C,-80 °C

Storage Comment: Antibody with azide - store at 2 to 8 °C. Antibody is stable for 24 months. Non-hazardous. Also available WITHOUT BSA & azide at 1.0mg/ml.

Expiry Date: 24 months

Target Details for TOM1L1

Target: TOM1L1 (Target of Myb1 (Chicken)-Like 1 (TOM1L1))

Alternative Name: TOM1L1

Background: 2310045L10Rik, C80573, OK/KNS CL.3, Src activating and signaling molecule, SRCASM, Target of Myb like protein 1, Target of myb1 (chicken) homolog like 1, Target of myb1 (chicken) like 1, TOM1 like protein 1, TOM1L1 protein,TOM1L1 (Target of Myb1 Like 1 Membrane Trafficking Protein)
Cellular localisation: Golgi apparatus > Golgi stack. Endosome membrane.

Molecular Weight: 53kDa.

Gene ID: 10040, 153504

UniProt: O75674