Recombinant CD21 antibody (C-Term)

Catalog No. ABIN7126254

The Rabbit Monoclonal anti-CD21 antibody has been validated for StM. It is suitable to detect CD21 in samples from Human.

Quick Overview for Recombinant CD21 antibody (C-Term) (ABIN7126254)

Target: CD21 (CR2) (Complement Component (3d/Epstein Barr Virus) Receptor 2 (CR2))

Antibody Type: Recombinant Antibody

Reactivity: Human

Host: Rabbit

Clonality: Monoclonal

Conjugate: This CD21 antibody is un-conjugated

Application: Staining Methods (StM)

Product Details anti-CD21 Antibody

Binding Specificity: C-Term

Specificity: CD21 also known as complement C3d receptor, Epstein-Barr virus receptor, and complement receptor type 2 (CR2), is a protein that in humans is encoded by the CR2 gene. This protein is involved in the complement system. It binds to iC3b (inactive derivative of C3b), C3dg, or C3d. B cells have CR2 receptors on their surfaces, allowing the complement system to play a role in B-cell activation and maturation.It is expressed by follicular dendritic cells (FDC) and mature B cells, as well as by several types of epithelial cells. CD21 is useful in the identification of follicular dendritic cell matrix found in normal lymph node and tonsillar tissue, and also useful in identifying abnormal.

Cross-Reactivity (Details): Human.

Purification: 1.0mg/ml of Ab purified from Bioreactor by Protein A/G.

Immunogen: Synthetic peptide corresponding to CD21 residues within aa933-C terminal of CD21.

Isotype: IgG

Application Details

Application Notes:

Known_Application: DilutionsImmunohistochemistry (Formalin-fixed) (1-2 μg/mL for 30 minutes at RT)(Staining of formalin-fixed tissues requires heating tissue sections in 10 mM Tris with 1 mM EDTA, pH 9.0, for 45 min at 95 °C followed by cooling at RT for 20 minutes)Optimal dilution for a specific application should be determined.

Positive_Control: Human tonsil tissue.

Restrictions: For Research Use only

Handling

Concentration: 1.0 mg/mL

Buffer: Prepared in 10 mM PBS, WITHOUT BSA and Azide.

Preservative: Azide free

Storage: -20 °C,-80 °C

Storage Comment: Antibody without azide - store at -20 to -80 °C. Antibody is stable for 24 months. Non-hazardous.

Expiry Date: 24 months

Target Details for CD21

Target: CD21 (CR2) (Complement Component (3d/Epstein Barr Virus) Receptor 2 (CR2))

Alternative Name: CR2

Background: CD21, Complement C3d receptor (C3DR), Complement Receptor type 2 (CR2), CVID7, EBV receptor, EBV-R, Epstein-Barr virus receptor, EVBR, SLEB9,CD21 (Mature B-Cell & Follicular Dendritic Cell Marker)
Cellular localisation: Cell Surface

Molecular Weight: 140kDa

Gene ID: 1380, 445757

UniProt: P20023

Pathways: Complement System