CTBP2 antibody
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- Target See all CTBP2 Antibodies
- CTBP2 (C-terminal Binding Protein 2 (CTBP2))
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Reactivity
- Human
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Host
- Mouse
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Clonality
- Monoclonal
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Conjugate
- This CTBP2 antibody is un-conjugated
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Application
- Immunofluorescence (IF), Flow Cytometry (FACS)
- Specificity
- The gene CTBP2 (C-terminal binding protein 2) encodes a member of the CtBP-family. The gene is mapped to human chromosome 21q21.3. It is found to be expressed ubiquitously, with higher expression in the heart, skeletal muscle, and pancreas. The gene CTBP2 (C-terminal binding protein 2) encodes a protein that functions as a transcriptional co-repressor of several tumor suppressor genes resulting in enhanced cancer cell migration and invasion. Its expression is found to be upregulated in hepatocellular carcinoma (HCC). It may be a potential prognostic marker for post liver resection HCC. It is involved in several types of tumor initiation, progression and response to therapy. It is found to interact with the C-terminal region of adenovirus type 2/5 E1A protein, a region that negatively regulates tumorigenicity and the extent of oncogenic transformation.
- Cross-Reactivity (Details)
- Human
- Purification
- 1.0mg/ml of Ab purified from Bioreactor by Protein A/G.
- Immunogen
- Recombinant full-length human CTBP2 protein
- Isotype
- IgG2b
- Top Product
- Discover our top product CTBP2 Primary Antibody
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- Application Notes
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Known_Application: Flow Cytometry (1-2 μg/million cells), Immunofluorescence (1-2 μg/mL), ,Optimal dilution for a specific application should be determined.
Positive_Control: Molt-4 or HeLa cells.
- Restrictions
- For Research Use only
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- Concentration
- 1.0 mg/mL
- Buffer
- Prepared in 10 mM PBS, WITHOUT BSA and Azide.
- Preservative
- Azide free
- Storage
- -20 °C,-80 °C
- Storage Comment
- Antibody without azide - store at -20 to -80 °C. Antibody is stable for 24 months. Non-hazardous.
- Expiry Date
- 24 months
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- Target
- CTBP2 (C-terminal Binding Protein 2 (CTBP2))
- Alternative Name
- CTBP2 (CTBP2 Products)
- Background
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C-terminal-binding protein 2 (CTBP2), Ribeye,CTBP2 (C-terminal binding protein 2)
Cellular localisation: Nucleus. Cell junction > synapse. - Molecular Weight
- 95.2kDa
- Gene ID
- 1488, 501345
- UniProt
- P56545
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