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CTBP2 antibody

CTBP2 Reactivity: Human IF, FACS Host: Mouse Monoclonal unconjugated
Catalog No. ABIN7126266
  • Target See all CTBP2 Antibodies
    CTBP2 (C-terminal Binding Protein 2 (CTBP2))
    Reactivity
    • 49
    • 16
    • 15
    • 6
    • 4
    • 4
    • 4
    • 3
    • 3
    • 3
    • 3
    • 2
    • 2
    • 1
    • 1
    Human
    Host
    • 43
    • 6
    Mouse
    Clonality
    • 46
    • 3
    Monoclonal
    Conjugate
    • 37
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This CTBP2 antibody is un-conjugated
    Application
    • 42
    • 24
    • 19
    • 8
    • 6
    • 6
    • 3
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    Immunofluorescence (IF), Flow Cytometry (FACS)
    Specificity
    The gene CTBP2 (C-terminal binding protein 2) encodes a member of the CtBP-family. The gene is mapped to human chromosome 21q21.3. It is found to be expressed ubiquitously, with higher expression in the heart, skeletal muscle, and pancreas. The gene CTBP2 (C-terminal binding protein 2) encodes a protein that functions as a transcriptional co-repressor of several tumor suppressor genes resulting in enhanced cancer cell migration and invasion. Its expression is found to be upregulated in hepatocellular carcinoma (HCC). It may be a potential prognostic marker for post liver resection HCC. It is involved in several types of tumor initiation, progression and response to therapy. It is found to interact with the C-terminal region of adenovirus type 2/5 E1A protein, a region that negatively regulates tumorigenicity and the extent of oncogenic transformation.
    Cross-Reactivity (Details)
    Human
    Purification
    1.0mg/ml of Ab purified from Bioreactor by Protein A/G.
    Immunogen
    Recombinant full-length human CTBP2 protein
    Isotype
    IgG2b
    Top Product
    Discover our top product CTBP2 Primary Antibody
  • Application Notes

    Known_Application: Flow Cytometry (1-2 μg/million cells), Immunofluorescence (1-2 μg/mL), ,Optimal dilution for a specific application should be determined.

    Positive_Control: Molt-4 or HeLa cells.

    Restrictions
    For Research Use only
  • Concentration
    1.0 mg/mL
    Buffer
    Prepared in 10 mM PBS, WITHOUT BSA and Azide.
    Preservative
    Azide free
    Storage
    -20 °C,-80 °C
    Storage Comment
    Antibody without azide - store at -20 to -80 °C. Antibody is stable for 24 months. Non-hazardous.
    Expiry Date
    24 months
  • Target
    CTBP2 (C-terminal Binding Protein 2 (CTBP2))
    Alternative Name
    CTBP2 (CTBP2 Products)
    Background
    C-terminal-binding protein 2 (CTBP2), Ribeye,CTBP2 (C-terminal binding protein 2)
    Cellular localisation: Nucleus. Cell junction > synapse.
    Molecular Weight
    95.2kDa
    Gene ID
    1488, 501345
    UniProt
    P56545
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