FOXB1 antibody

Catalog No. ABIN7126475

Product Details anti-FOXB1 Antibody

Target: FOXB1 (Forkhead Box B1 (FOXB1))

Reactivity: Human

Host: Mouse

Clonality: Monoclonal

Conjugate: This FOXB1 antibody is un-conjugated

Application: ELISA, Immunofluorescence (IF), Coating (Coat), Flow Cytometry (FACS), Immunoprecipitation (IP)

Specificity: The Forkhead-box (FOX) genes comprise a superfamily of at least 43 members that encode proteins which are involved in transcriptional regulation and may be associated with the pathogenesis of various cancers. FOXB1 (forkhead box B1), also known as FKH5 or HFKH-5, and FOXB2 (forkhead box B2) are members of the FOX family and each contain one forkhead DNA-binding domain. Both FOXB1 and FOXB2 localize to the nucleus where they are thought to function as transcription factors that can bind to DNA via their forkhead domains. In mice, defects in the gene encoding FOXB1 are associated with retarded development of the central nervous system (CNS), suggesting that FOXB1 may play a role in CNS organization and function.

Cross-Reactivity (Details): Human.

Purification: 1.0mg/ml of Ab purified from Bioreactor by Protein A/G.

Immunogen: Recombinant full-length human FOXB1protein

Isotype: IgG1

Application Details

Application Notes:

Known_Application: ELISA (For coating, order antibody without BSA), ,Immunoprecipitation (1-2 μg per 100-500 μg of total protein (1 mL of cell lysate)), ,Flow Cytometry (1-2 μg/million cells), Immunofluorescence (1-2 μg/mL), ,Optimal dilution for a specific application should be determined.

Positive_Control: HeLa or HepG2 cells.

Restrictions: For Research Use only

Handling

Concentration: 1.0 mg/mL

Buffer: Prepared in 10 mM PBS, WITHOUT BSA and Azide.

Preservative: Azide free

Storage: -20 °C,-80 °C

Storage Comment: Antibody without azide - store at -20 to -80 °C. Antibody is stable for 24 months. Non-hazardous.

Expiry Date: 24 months

Target Details for FOXB1

Target: FOXB1 (Forkhead Box B1 (FOXB1))

Alternative Name: FOXB1 (FOXB1 Products)

Synonyms: FKH5 antibody, HFKH-5 antibody, C43 antibody, Fkh5 antibody, Foxb1a antibody, Foxb1b antibody, Hfh-e5.1 antibody, Mf3 antibody, Twh antibody, FOXB1 antibody, fkh-5 antibody, fkh5 antibody, hfkh-5 antibody, xfkh-5 antibody, foxB1 antibody, foxB antibody, forkhead box B1 antibody, forkhead box B1 S homeolog antibody, FOXB1 antibody, Foxb1 antibody, foxb1 antibody, foxB1 antibody, foxb1.S antibody

Background: FKH 5, FKH5, Forkhead box B1, Forkhead box protein B1, FOX B1, FOXB 1, HFKH 5, HFKH-5, HFKH5, Transcription factor FKH 5, Transcription factor FKH5,FOXB1 (Transcription Factor)
Cellular localisation: Nucleus.

Molecular Weight: 35kDa

Gene ID: 27023, 734475

UniProt: Q99853