FOXB2 antibody (AA 1-200)

Catalog No. ABIN7126716

The Mouse Monoclonal anti-FOXB2 antibody is suitable to detect FOXB2 in samples from Human. It has been validated for ELISA and FACS.

Quick Overview for FOXB2 antibody (AA 1-200) (ABIN7126716)

Target: FOXB2 (Forkhead Box B2 (FOXB2))

Reactivity: Human

Host: Mouse

Clonality: Monoclonal

Conjugate: This FOXB2 antibody is un-conjugated

Application: ELISA, Flow Cytometry (FACS)

Clone: PCRP-FOXB2-2B2

Product Details anti-FOXB2 Antibody

Binding Specificity: AA 1-200

Purpose: FOXB2 (Transcription Factor) Antibody

Specificity: The Forkhead-box (FOX) genes comprise a superfamily of at least 43 members that encode proteins which are involved in transcriptional regulation and may be associated with the pathogenesis of various cancers. FOXB1 (forkhead box B1), also known as FKH5 or HFKH-5, and FOXB2 (forkhead box B2) are members of the FOX family and each contain one forkhead DNA-binding domain. Both FOXB1 and FOXB2 localize to the nucleus where they are thought to function as transcription factors that can bind to DNA via their forkhead domains. In mice, defects in the gene encoding FOXB1 are associated with retarded development of the central nervous system (CNS), suggesting that FOXB1 may play a role in CNS organization and function.

Cross-Reactivity (Details): Human. Predicted to react in Mouse and Rat.

Purification: 200ug/ml of Ab purified from Bioreactor Concentrate by Protein A/G.

Immunogen: Recombinant fragment (around aa1-200) of human FOXB2 protein (exact sequence is proprietary)

Isotype: IgG2a

Application Details

Application Notes:

Known_Application: ELISA (For coating, order antibody without BSA), ,Immunoprecipitation (1-2 μg per 100-500 μg of total protein (1 mL of cell lysate)), ,Flow Cytometry (1-2 μg/million cells), ,Optimal dilution for a specific application should be determined.

Positive_Control: HeLa or HepG2 cells.

Restrictions: For Research Use only

Handling

Concentration: 1.0 mg/mL

Buffer: Prepared in 10  mM PBS

Preservative: Azide free

Storage: -20 °C,-80 °C

Storage Comment: Antibody with azide - store at 2 to 8 °C. Antibody without azide - store at -20 to -80 °C. Antibody is stable for 24 months. Non-hazardous. No MSDS required.

Expiry Date: 24 months

Target Details for FOXB2

Target: FOXB2 (Forkhead Box B2 (FOXB2))

Alternative Name: FOXB2

Background:

bA159H20.4, Forkhead box B2, Forkhead box protein B2, FOXB 2, Foxb2

HeLa or HepG2 cells.

Molecular Weight: 45.58kDa

Gene ID: 442425, 553843

UniProt: Q5VYV0