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Recombinant Prolactin antibody (AA 63-201)

The Rabbit Monoclonal anti-Prolactin antibody has been validated for IHC (f). It is suitable to detect Prolactin in samples from Human.
Catalog No. ABIN7126839

Quick Overview for Recombinant Prolactin antibody (AA 63-201) (ABIN7126839)

Target

See all Prolactin (PRL) Antibodies
Prolactin (PRL)

Antibody Type

Recombinant Antibody

Reactivity

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Human

Host

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Rabbit

Clonality

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Monoclonal

Conjugate

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This Prolactin antibody is un-conjugated

Application

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Immunohistochemistry (Formalin-fixed Sections) (IHC (f))
  • Binding Specificity

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    AA 63-201

    Specificity

    Prolactin is a growth factor that is secreted by the anterior pituitary. It is necessary for the proliferation and differentiation of the mammary glands. Prolactin is useful in the classification of pituitary tumors and study of pituitary disease. It also plays a role in the development of mammary cancer, functioning dually as a mitogen and a differentiating agent.

    Cross-Reactivity (Details)

    Human.

    Purification

    1.0mg/ml of Ab purified from Bioreactor by Protein A/G.

    Immunogen

    Recombinant fragment of human Prolactin (PRL) protein (around aa 63-201) (exact sequence is proprietary)

    Isotype

    IgG
  • Application Notes

    Known_Application: Immunohistochemistry (Formalin-fixed) (1-2 μg/mL for 30 minutes at RT),(Staining of formalin-fixed tissues requires heating tissue sections in 10 mM Tris with 1 mM EDTA, pH 9.0, for 45 min at 95 °C followed by cooling at RT for 20 minutes),Optimal dilution for a specific application should be determined.

    Positive_Control: Pituitary tissue. Pituitary lysate.

    Restrictions

    For Research Use only
  • Concentration

    1.0 mg/mL

    Buffer

    Prepared in 10 mM PBS, WITHOUT BSA and Azide.

    Preservative

    Azide free

    Storage

    -20 °C,-80 °C

    Storage Comment

    Antibody without azide - store at -20 to -80 °C. Antibody is stable for 24 months. Non-hazardous.

    Expiry Date

    24 months
  • Target

    Prolactin (PRL)

    Alternative Name

    PRL

    Background

    Decidual prolactin, GHA1, Growth hormone A1, Lactogenic hormone, Luteotropic hormone, Mammotropin, PRL, Prolactin, Prolactin precursor,Prolactin (Pituitary Tumor Marker)
    Cellular localisation: Secreted.

    Molecular Weight

    27kDa

    Gene ID

    5617, 1905

    Pathways

    JAK-STAT Signaling, Peptide Hormone Metabolism, Response to Growth Hormone Stimulus, Protein targeting to Nucleus
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